Background The increase in sedentary behavior (SB) in children and adolescents is one of
the major threats to global public health, and the relationship between physical activity (PA) …

Obesity is strongly related to leptin resistance that refers to the state in which leptin fails to
inhibit appetite, enhance energy expenditure and regulate glycolipid metabolism, whereas …

Adipokines dysregulation, the main reason for cognitive impairments (CI) induced by
diabetes, shows a sex-dependent pattern inherently and in response to exercise. This study …

With the increasingly severe situation of obesity and population aging, there is growing
concern about sarcopenia obesity (SO). SO refers to the coexistence of obesity and …

Obesity and overnutrition induce inflammation, leptin-, and insulin resistance in the
hypothalamus. The mediobasal hypothalamus responds to exercise enabling critical …

Simple Summary Our growing aging population and increased prevalence of obesity have
become an emerging health problem as these conditions lead to the development of related …

TRB3, a mammalian homolog of Drosophila tribbles, plays an important role in multiple
tissues and it has been implicated in stress response regulation and metabolic control …

The hypothalamus plays a critical role in the control of food consumption and energy
expenditure. Fatty diets can elicit an inflammatory response in specific hypothalamic cells …

The obesity is a result of energy imbalance and the increase in thermogenesis seems an
interesting alternative for the treatment of this disease. The mechanism of energy …

Background APPL1, an adapter protein, interact directly with adiponectin receptors
mediating adiponectin signaling and acting as a critical regulator of the crosstalk between …