Epidemiology, diagnosis, and antimicrobial treatment of acute bacterial meningitis

MC Brouwer, AR Tunkel… - Clinical microbiology …, 2010 - Am Soc Microbiol
The epidemiology of bacterial meningitis has changed as a result of the widespread use of
conjugate vaccines and preventive antimicrobial treatment of pregnant women. Given the …

AGA technical review on perianal Crohn's disease

WJ Sandborn, VW Fazio, BG Feagan, SB Hanauer - Gastroenterology, 2003 - Elsevier
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Granulomatous infectious diseases associated with tumor necrosis factor antagonists

RS Wallis, MS Broder, JY Wong… - Clinical infectious …, 2004 - academic.oup.com
The relationship between the use of tumor necrosis factor antagonists and onset of
granulomatous infection was examined using data collected through the Adverse Event …

The safety profile of infliximab in patients with Crohn's disease: the Mayo clinic experience in 500 patients

JF Colombel, EV Loftus Jr, WJ Tremaine, LJ Egan… - Gastroenterology, 2004 - Elsevier
Background & Aims: The aim of this study was to evaluate the short-and long-term safety of
infliximab in patients with Crohn's disease in clinical practice. Methods: The medical records …

New drugs for rheumatoid arthritis

NJ Olsen, CM Stein - New England Journal of Medicine, 2004 - Mass Medical Soc
Rheumatoid arthritis affects about 1 percent of the US population and can cause irreversible
joint deformities and functional impairment. Although the cause of this autoimmune disease …

Infection risk associated with anti-TNF-α agents: a review

G Murdaca, F Spanò, M Contatore… - Expert opinion on …, 2015 - Taylor & Francis
Introduction: TNF-α is a pro-inflammatory cytokine known to a have a key role in the
pathogenesis of chronic immune-mediated diseases. TNF-α inhibitors can be administered …

Listeria monocytogenes infection as a complication of treatment with tumor necrosis factor α–neutralizing agents

NR Slifman, SK Gershon, JH Lee… - Arthritis & …, 2003 - Wiley Online Library
Objective Tumor necrosis factor α (TNFα) has been implicated in the pathogenesis of certain
inflammatory diseases. Two TNFα‐neutralizing agents are licensed in the US. Infliximab is …

Treatment of rheumatoid arthritis

A Gaffo, KG Saag, JR Curtis - American journal of health-system …, 2006 - academic.oup.com
Purpose. Current and investigational treatments of rheumatoid arthritis (RA) are described.
Summary. The current therapies used to treat RA include nonsteroidal antiinflammatory …

Tumor necrosis factor antagonists: different kinetics and/or mechanisms of action may explain differences in the risk for developing granulomatous infection

DE Furst, R Wallis, M Broder… - Seminars in arthritis and …, 2006 - Elsevier
OBJECTIVE: Tumor necrosis factor (TNF) antagonists fall into 2 classes: etanercept (ETA) is
a soluble TNF receptor, while infliximab (INF) and adalimumab (ADA) are monoclonal …

Infliximab in the treatment of Crohn's disease: a user's guide for clinicians

WJ Sandborn, SB Hanauer - … journal of the American College of …, 2002 - journals.lww.com
Induction therapy with infliximab is indicated for treatment of signs and symptoms, and
induction and maintenance of remission in patients with moderate to severely active …