Harnessing Guanidinium and Imidazole Functional Groups: A Dual-Charged Polymer Strategy for Enhanced Gene Delivery
PP Mapfumo, LS Reichel, K Leer, J Egger… - ACS Macro …, 2024 - ACS Publications
Histidine and arginine are two amino acids that exhibit beneficial properties for gene
delivery. In particular, the imidazole group of histidine facilitates endosomal release, while …
delivery. In particular, the imidazole group of histidine facilitates endosomal release, while …
PEGDA microencapsulated allogeneic islets reverse canine diabetes without immunosuppression
S Harrington, F Karanu, K Ramachandran, SJ Williams… - Plos one, 2022 - journals.plos.org
Background Protection of islets without systemic immunosuppression has been a long-
sought goal in the islet transplant field. We conducted a pilot biocompatibility/safety study in …
sought goal in the islet transplant field. We conducted a pilot biocompatibility/safety study in …
Poly(N-acryloylmorpholine) Nanogels as Promising Materials for Biomedical Applications: Low Protein Adhesion and High Colloidal Stability
TMP Neumann-Tran, C López-Iglesias… - ACS Applied Polymer …, 2023 - ACS Publications
Poly (N-acryloylmorpholine)(P (NAM))-based materials have been developed to prevent
protein adhesion to surfaces due to their biocompatibility and protein-repellent properties …
protein adhesion to surfaces due to their biocompatibility and protein-repellent properties …
Dually Modified Cellulose as a Non-Viral Vector for the Delivery and Uptake of HDAC3 siRNA
J Hülsmann, H Lindemann, J Wegener, M Kühne… - Pharmaceutics, 2023 - mdpi.com
RNA interference can be applied to different target genes for treating a variety of diseases,
but an appropriate delivery system is necessary to ensure the transport of intact siRNAs to …
but an appropriate delivery system is necessary to ensure the transport of intact siRNAs to …