Potential therapeutic targets of epigallocatechin gallate (EGCG), the most abundant catechin in green tea, and its role in the therapy of various types of cancer

SA Almatroodi, A Almatroudi, AA Khan, FA Alhumaydhi… - Molecules, 2020 - mdpi.com
Epigallocatechin-3-gallate (EGCG), an active compound of green tea and its role in
diseases cure and prevention has been proven. Its role in diseases management can be …

[HTML][HTML] Antioxidant responses and cellular adjustments to oxidative stress

C Espinosa-Diez, V Miguel, D Mennerich, T Kietzmann… - Redox biology, 2015 - Elsevier
Redox biological reactions are now accepted to bear the Janus faceted feature of promoting
both physiological signaling responses and pathophysiological cues. Endogenous …

Anticancer efficacy of polyphenols and their combinations

A Niedzwiecki, MW Roomi, T Kalinovsky, M Rath - Nutrients, 2016 - mdpi.com
Polyphenols, found abundantly in plants, display many anticarcinogenic properties including
their inhibitory effects on cancer cell proliferation, tumor growth, angiogenesis, metastasis …

Cellular defensive mechanisms of tea polyphenols: Structure-activity relationship

VL Truong, WS Jeong - International journal of molecular sciences, 2021 - mdpi.com
Tea is particularly rich in polyphenols, including catechins and theaflavins, thearubigins,
flavonols, and phenolic acids, which are believed to contribute to the health benefits of tea …

Dietary phenolics: chemistry, bioavailability and effects on health

A Crozier, IB Jaganath, MN Clifford - Natural product reports, 2009 - pubs.rsc.org
Covering: up to the end of 2008 There is much epidemiological evidence that diets rich in
fruit and vegetables can reduce the incidence of non-communicable diseases such as …

Natural phenolic compounds from medicinal herbs and dietary plants: potential use for cancer prevention

WY Huang, YZ Cai, Y Zhang - Nutrition and cancer, 2009 - Taylor & Francis
Natural phenolic compounds play an important role in cancer prevention and treatment.
Phenolic compounds from medicinal herbs and dietary plants include phenolic acids …

The Nrf2-ARE signaling pathway: An update on its regulation and possible role in cancer prevention and treatment

V Krajka-Kuźniak, J Paluszczak… - Pharmacological …, 2017 - Elsevier
Nrf2 acts as a sensor of oxidative or electrophilic stress and prevents genome instability. The
activation of Nrf2 signaling induces ARE-dependent expression of detoxifying and …

Cancer chemoprevention with dietary phytochemicals

YJ Surh - Nature Reviews Cancer, 2003 - nature.com
Chemoprevention refers to the use of agents to inhibit, reverse or retard tumorigenesis.
Numerous phytochemicals derived from edible plants have been reported to interfere with a …

Flavonoids: antioxidants or signalling molecules?

RJ Williams, JPE Spencer, C Rice-Evans - Free radical biology and …, 2004 - Elsevier
Many studies are accumulating that report the neuroprotective, cardioprotective, and
chemopreventive actions of dietary flavonoids. While there has been a major focus on the …

Tea catechins and polyphenols: health effects, metabolism, and antioxidant functions

JV Higdon, B Frei - 2003 - Taylor & Francis
Increasing interest in the health benefits of tea has led to the inclusion of tea extracts in
dietary supplements and functional foods. However, epidemiologic evidence regarding the …