Molecular approaches for the improvement of under-researched tropical fruit trees: Jackfruit, guava, and custard apple
Fruit trees are important as additional sources of revenue and are important diet
supplements. Besides yielding edible fruits, there are several other useful products available …
supplements. Besides yielding edible fruits, there are several other useful products available …
Entropy-enthalpy compensation in the methyl 5-thio-α-d-galactopyranoside–Jacalin interaction
D Ahiadorme, D Crich - Carbohydrate Research, 2025 - Elsevier
Abstract Methyl 5-thio-α-d-galactopyranoside was synthesized and found to have a more
favorable enthalpy of binding to Jacalin than methyl α-d-galactopyranoside, which is …
favorable enthalpy of binding to Jacalin than methyl α-d-galactopyranoside, which is …
Targeting the glycan of receptor binding domain with jacalin as a novel approach to develop a treatment against COVID-19
S Rajendaran, A Jothi… - Royal Society Open …, 2020 - royalsocietypublishing.org
In silico analysis revealed that a lectin, jacalin from jackfruit seeds, recognizes a
glycosylated region of the receptor-binding domain (RBD) of SARS-CoV2. Jacalin binding …
glycosylated region of the receptor-binding domain (RBD) of SARS-CoV2. Jacalin binding …
Ligand binding and retention in snake gourd seed lectin (SGSL). A crystallographic, thermodynamic and molecular dynamics study
Snake gourd seed lectin (SGSL) is a non-toxic homolog of type II ribosome-inactivating
proteins (RIPs) which contain a catalytic domain and a lectin domain. Isothermal titration …
proteins (RIPs) which contain a catalytic domain and a lectin domain. Isothermal titration …
Distortion of the ligand molecule as a strategy for modulating binding affinity: further studies involving complexes of Jacalin with β‐substituted disaccharides
Crystal structures of jacalin in complex with GlcNAc β‐(1, 3) Gal‐β‐OMe and Gal β‐(1, 3) Gal‐
β‐OMe have been determined. The binding of the ligands to jacalin is similar to that of …
β‐OMe have been determined. The binding of the ligands to jacalin is similar to that of …
Effect of linkage on the location of reducing and nonreducing sugars bound to jacalin
The crystal structures of jacalin complexed with Gal α‐(1, 4) Gal and Gal α‐(1, 3) Gal β‐(1, 4)
Gal have been determined with the primary objective of exploring the effect of linkage on the …
Gal have been determined with the primary objective of exploring the effect of linkage on the …
Mevo lectin specificity toward high-mannose structures with terminal αMan (1, 2) αMan residues and its implication to inhibition of the entry of Mycobacterium …
Mannose-binding lectins can specifically recognize and bind complex glycan structures on
pathogens and have potential as antiviral and antibacterial agents. We previously reported …
pathogens and have potential as antiviral and antibacterial agents. We previously reported …
Structural biology of plant lectins and macromolecular crystallography in India
Earnest attempts at initiating macromolecular crystallography, which is central to modern
biology, started in India in the 1970s. The most important component of the efforts was on …
biology, started in India in the 1970s. The most important component of the efforts was on …
Structural studies on a non-toxic homologue of type II RIPs from bitter gourd: Molecular basis of non-toxicity, conformational selection and glycan structure
The structures of nine independent crystals of bitter gourd seed lectin (BGSL), a non-toxic
homologue of type II RIPs, and its sugar complexes have been determined. The four-chain …
homologue of type II RIPs, and its sugar complexes have been determined. The four-chain …
New structural insights into anomeric carbohydrate recognition by frutalin: an α-d-galactose-binding lectin from breadfruit seeds
Frutalin (FTL) is a multiple-binding lectin belonging to the jacalin-related lectin (JRL) family
and derived from Artocarpus incisa (breadfruit) seeds. This lectin specifically recognizes and …
and derived from Artocarpus incisa (breadfruit) seeds. This lectin specifically recognizes and …