Mitochondria are cellular organelles responsible for generation of chemical energy in the
process called oxidative phosphorylation. They originate from a bacterial ancestor and …

Mitochondria are the major source of ATP in the cell. Five multi-subunit complexes in the
inner membrane of the organelle are involved in the oxidative phosphorylation required for …

Mitochondria are essential organelles of endosymbiotic origin that are responsible for
oxidative phosphorylation within eukaryotic cells. Independent evolution between species …

The assembly of mitochondrial oxidative phosphorylation (OXPHOS) complexes is an
intricate process, which—given their dual-genetic control—requires tight co-regulation of two …

Protein synthesis in mammalian mitochondria produces 13 proteins that are essential
subunits of the oxidative phosphorylation complexes. This review provides a detailed outline …

Mitochondrial disorders are a heterogeneous group of often multisystemic and early fatal
diseases, which are amongst the most common inherited human diseases. These disorders …

Oxidative phosphorylation (OXPHOS) is the mechanism whereby ATP, the major energy
source for the cell, is produced by harnessing cellular respiration in the mitochondrion. This …

Mitochondria control life and death in eukaryotic cells. Harboring a unique circular genome,
a by‐product of an ancient endosymbiotic event, mitochondria maintains a specialized and …

The mitochondrial translation system originates from a bacterial ancestor but has
substantially diverged in the course of evolution. Here, we use single-particle cryo-electron …

Translation elongation is a key step of protein synthesis, during which the nascent
polypeptide chain extends by one amino acid residue during one elongation cycle. More …