Advances in oral drug delivery systems: Challenges and opportunities

J Lou, H Duan, Q Qin, Z Teng, F Gan, X Zhou, X Zhou - Pharmaceutics, 2023 - mdpi.com
The oral route is the most preferred route for systemic and local drug delivery. However, the
oral drug delivery system faces the harsh physiological and physicochemical environment of …

Advancements in the pharmaceutical applications of probiotics: Dosage forms and formulation technology

KC Baral, R Bajracharya, SH Lee… - International journal of …, 2021 - Taylor & Francis
Probiotics have demonstrated their high potential to treat and/or prevent various diseases
including neurodegenerative disorders, cancers, cardiovascular diseases, and inflammatory …

Oral core–shell nanoparticles embedded in hydrogel microspheres for the efficient site-specific delivery of magnolol and enhanced antiulcerative colitis therapy

X Wang, H Gu, H Zhang, J Xian, J Li, C Fu… - … Applied Materials & …, 2021 - ACS Publications
Although magnolol (Mag), an anti-inflammatory natural compound, has been demonstrated
to play protective effects on ulcerative colitis (UC), its application as an alternative …

Shape memory materials and 4D printing in pharmaceutics

A Melocchi, M Uboldi, M Cerea, A Foppoli… - Advanced Drug Delivery …, 2021 - Elsevier
Shape memory materials (SMMs), including alloys and polymers, can be programmed into a
temporary configuration and then recover the original shape in which they were processed …

Chitosan-based oral colon-specific delivery systems for polyphenols: recent advances and emerging trends

S Chen, H Zhu, Y Luo - Journal of Materials Chemistry B, 2022 - pubs.rsc.org
Oral colon-targeted delivery systems (OCDSs) have attracted great attention in the delivery
of active compounds targeted to the colon for the treatment of colon and non-colon diseases …

Oral peptide delivery: Challenges and the way ahead

SK Dubey, S Parab, N Dabholkar, M Agrawal… - Drug discovery today, 2021 - Elsevier
Highlights•Oral route of administration is the preferred route for drug delivery.•Dosage form
designing plays an essential role in oral peptide delivery.•Preclinical and clinical aspects of …

[HTML][HTML] Nanotechnology for inflammatory bowel disease management: Detection, imaging and treatment

M Barani, A Rahdar, S Sargazi, MS Amiri… - Sensing and bio …, 2021 - Elsevier
Inflammatory bowel disease (IBD) is a group of intestinal disorders which cause prolonged
digestive tract inflammation. The early diagnosis of IBD through the detection of its …

Harnessing the dual role of polysaccharides in treating gastrointestinal diseases: As therapeutics and polymers for drug delivery

L Corrie, M Gulati, A Awasthi, S Vishwas, J Kaur… - Chemico-Biological …, 2022 - Elsevier
Polysaccharides (PS) represent a broad class of polymer-based compounds that have been
extensively researched as therapeutics and excipients for drug delivery. As pharmaceutical …

Strategic developments in polymer-functionalized liposomes for targeted colon cancer therapy: an updated review of clinical trial data and future horizons

S Sharma, M Chakraborty, D Yadav, A Dhullap… - …, 2024 - ACS Publications
Liposomes, made up of phospholipid bilayers, are efficient nanocarriers for drug delivery
because they can encapsulate both hydrophilic and lipophilic drugs. Conventional cancer …

[HTML][HTML] Optimization study of combined enteric and time-dependent polymethacrylates as a coating for colon targeted delivery of 5-ASA pellets in rats with ulcerative …

HS Sardou, A Akhgari, AH Mohammadpour… - European Journal of …, 2022 - Elsevier
Abstract Formulation design for colon-specific delivery of 5-aminosalicylic acid (5-ASA)
could bring some therapeutic benefits in the treatment of ulcerative colitis (UC). In the current …