Update on psoriasis immunopathogenesis and targeted immunotherapy

SK Mahil, F Capon, JN Barker - Seminars in immunopathology, 2016 - Springer
Over recent years, significant progress has been made in characterisation of the underlying
pathogenic mechanisms in psoriasis, a common cutaneous disease that is associated with …

The roles of cells and cytokines in the pathogenesis of psoriasis

S Coimbra, A Figueiredo, E Castro… - International journal …, 2012 - Wiley Online Library
Psoriasis is considered an immune chronic disease in which T cells are accepted as
important. Nowadays, it is believed that psoriasis is most likely a T helper (Th) 1/Th17 …

Bifidobacterium infantis 35624 modulates host inflammatory processes beyond the gut

D Groeger, L O'Mahony, EF Murphy, JF Bourke… - Gut …, 2013 - Taylor & Francis
Certain therapeutic microbes, including Bifidobacteria infantis (B. infantis) 35624 exert
beneficial immunoregulatory effects by mimicking commensal-immune interactions; …

Serum Levels of TNF‐α, IFN‐γ, IL‐6, IL‐8, IL‐12, IL‐17, and IL‐18 in Patients With Active Psoriasis and Correlation With Disease Severity

O Arican, M Aral, S Sasmaz… - Mediators of inflammation, 2005 - Wiley Online Library
Recent progress in the understanding of psoriasis has shown that the regulation of local and
systemic cytokines plays an important role in its pathogenesis. The most often used …

[HTML][HTML] Treatment of autoimmunity: the impact of disease-modifying therapies in multiple sclerosis and comorbid autoimmune disorders

FF Konen, N Möhn, T Witte, M Schefzyk, M Wiestler… - Autoimmunity …, 2023 - Elsevier
More than 10 disease-modifying therapies (DMT) are approved by the European Medicines
Agency (EMA) and the US Food and Drug Administration (FDA) for the treatment of multiple …

New insights into different adipokines in linking the pathophysiology of obesity and psoriasis

Y Kong, S Zhang, R Wu, X Su, D Peng, M Zhao… - Lipids in health and …, 2019 - Springer
Psoriasis is a chronic, systemic, hyper-proliferative immune-mediated inflammatory skin
disease. The results of epidemiological investigations have shown that psoriasis affects …

Interleukin (IL)‐22, IL‐17, IL‐23, IL‐8, vascular endothelial growth factor and tumour necrosis factor‐α levels in patients with psoriasis before, during and after psoralen …

S Coimbra, H Oliveira, F Reis, L Belo… - British Journal of …, 2010 - academic.oup.com
Background Several cross‐sectional studies have shown that different cytokines and growth
factors are enhanced in psoriasis. Objectives We aimed to understand the role/relation of …

Treatment approaches to patients with multiple sclerosis and coexisting autoimmune disorders

T Brummer, T Ruck, SG Meuth… - Therapeutic …, 2021 - journals.sagepub.com
The past decades have yielded major therapeutic advances in many autoimmune conditions–
such as multiple sclerosis (MS)–and thus ushered in a new era of more targeted and …

The triad psoriasis–obesity–adipokine profile

S Coimbra, C Catarino… - Journal of the European …, 2016 - Wiley Online Library
Psoriasis is a chronic inflammatory skin disease, often associated with overweight/obesity.
The adipose tissue is a complex organ that secretes several adipokines, involved in the …

Pathogenesis of psoriasis in the “omic” era. Part I. Epidemiology, clinical manifestation, immunological and neuroendocrine disturbances

D Samotij, B Nedoszytko, J Bartosińska… - … in Dermatology and …, 2020 - termedia.pl
Psoriasis is a common, chronic, inflammatory, immune-mediated skin disease affecting
about 2% of the world's population. According to current knowledge, psoriasis is a complex …