PIWI-Interacting RNA in Drosophila: Biogenesis, Transposon Regulation, and Beyond

H Yamashiro, MC Siomi - Chemical reviews, 2017 - ACS Publications
PIWI-interacting RNAs (piRNAs) are germline-enriched small RNAs that control transposons
to maintain genome integrity. To achieve this, upon being processed from piRNA precursors …

Novel dimensions of piRNAs in cancer

Y Mei, D Clark, L Mao - Cancer letters, 2013 - Elsevier
Piwi-interacting RNAs (piRNAs), a newly identified class of small non-coding RNAs, direct
the Piwi-dependent transposon silencing, heterochromatin modification and germ cell …

Piwi Proteins and piRNAs step onto the systems biology stage

JP Clark, NC Lau - Systems biology of RNA binding proteins, 2014 - Springer
Animal germ cells are totipotent because they maintain a highly unique and specialized
epigenetic state for its genome. To accomplish this, germ cells express a rich repertoire of …