Global proteomics insights for a novel small compound targeting the non-integrin Laminin Receptor in a macrophage cell model

A Haffner, M Figueiredo Neto, CS Umbaugh… - Frontiers in Drug …, 2023 - frontiersin.org
Introduction: Monocytes and macrophages are the first barrier of the innate immune system,
which interact with agents causing osteoarthritis or other conditions, leading to the release of …

[HTML][HTML] RUNX1 在骨发育及骨相关疾病中的作用研究进展

子建潘, 雪儿周, 志炜曹, 剑潘 - Journal of Sichuan University …, 2024 - ncbi.nlm.nih.gov
Abstract RUNX1 是一种与造血系统发生密切相关的转录因子, 其基因突变在血液系统肿瘤,
特别是在急性髓系白血病的发生发展中起到重要的致病作用。 近年来研究表明, RUNX1 …

[HTML][HTML] Polyethylene glycol-stabilized cationic liposome encapsulating glucosamine sulfate: A promising nanoformulation for osteoarthritis therapy

X Liu, H Dai, Z Wang, C Huang, K Huang - AIP Advances, 2024 - pubs.aip.org
Osteoarthritis (OA) is a common orthopedic chronic disease, and the use of nanomaterials
as carriers is an effective way to realize slow and controlled release therapy for OA drugs. In …

Latest Findings on the Role of RUNX1 in Bone Development and Disorders

PAN Zijian, Z Xue'er, CAO Zhiwei… - JOURNAL OF SICHUAN …, 2024 - ykxb.scu.edu.cn
Runt-related transcription factor (RUNX1) is a transcription factor closely involved in
hematopoiesis. RUNX1 gene mutation plays an essential pathogenic role in the initiation …