Abstract Tripterygium wilfordii Hook F (TwHF)‐based therapy is among the most efficient and
crucial therapeutics for the treatment of rheumatoid arthritis (RA), which indicates that TwHF …

Abstract The interleukin (IL)-1 family of cytokines comprises 11 members, including 7 pro-
inflammatory agonists (IL-1α, IL-1β, IL-18, IL-33, IL-36α, IL-36β, IL-36γ) and 4 defined or …

IL‐37 is a unique member of the IL‐1 family of cytokines, which functions as a natural
suppressor of inflammatory and immune responses. Immune and non‐immune cells …

Psoriasis is a chronic systemic inflammatory disease causing erythematosus and scaly skin
plaques; up to 30% of patients with psoriasis develop Psoriatic Arthritis (PsA), which is …

IL‐37 is unique in the IL‐1 family in that unlike other members of the family, IL‐37 broadly
suppresses innate immunity. IL‐37 can be elevated in humans with inflammatory and …

Abstract T helper 17 (Th17) cells are important mediators of immune responses against
extracellular bacteria and fungi, and as such play critical regulatory roles in maintaining …

Necrotizing enterocolitis (NEC) is a severe, currently untreatable intestinal disease that
predominantly affects preterm infants and is driven by poorly characterized inflammatory …

Chronic kidney disease (CKD) is inherently an inflammatory condition, which ultimately
results in the development of end stage renal disease or cardiovascular events. Low-grade …

In recent years, the landscape of pro-and anti-inflammatory cytokines has rapidly expanded
with the identification of new members proven to be involved at different extent in the …

Immune cell plasticity has extensive implications in the pathogenesis and resolution of
metabolic disorders, cancers, autoimmune diseases and chronic inflammatory disorders …