Device-based therapies for arterial hypertension

L Lauder, M Azizi, AJ Kirtane, M Boehm… - Nature Reviews …, 2020 - nature.com
Arterial hypertension is the most prevalent modifiable risk factor associated with
cardiovascular morbidity and mortality. Although antihypertensive drugs are widely …

[HTML][HTML] Device-based therapy for hypertension

FL Ng, M Saxena, F Mahfoud, A Pathak… - Current Hypertension …, 2016 - Springer
Hypertension continues to be a major contributor to global morbidity and mortality, fuelled by
an abundance of patients with uncontrolled blood pressure despite the multitude of …

Renal denervation for treatment of ventricular arrhythmias: data from an International Multicenter Registry

C Ukena, F Mahfoud, S Ewen, A Bollmann… - Clinical Research in …, 2016 - Springer
Abstract Introduction Ventricular arrhythmias (VAs) in patients with chronic heart failure
(CHF) are sometimes refractory to antiarrhythmic drugs and cardiac ablation. This study …

Interventional procedures and future drug therapy for hypertension

MD Lobo, PA Sobotka, A Pathak - European heart journal, 2017 - academic.oup.com
Hypertension management poses a major challenge to clinicians globally once non-drug
(lifestyle) measures have failed to control blood pressure (BP). Although drug treatment …

Renal sympathetic denervation in Sweden: a report from the Swedish registry for renal denervation

S Völz, J Spaak, J Elf, C Jägrén, C Lundin… - Journal of …, 2018 - journals.lww.com
Background: Renal denervation (RDN) is a catheter-based intervention to treat patients with
resistant hypertension. The biological effects of RDN are not fully understood, and …

Hypertension: history and development of established and novel treatments

M Wolf, S Ewen, F Mahfoud, M Boehm - Clinical Research in Cardiology, 2018 - Springer
Background This article summarizes the emerging field of hypertension over the last
decades. It covers paradigm shifts on hypertension from an undefined cardiovascular …

Joint UK societies' 2019 consensus statement on renal denervation

MD Lobo, ASP Sharp, V Kapil, J Davies, MA de Belder… - Heart, 2019 - heart.bmj.com
Improved and durable control of hypertension is a global priority for healthcare providers
and policymakers. There are several lifestyle measures that are proven to result in improved …

Blood pressure response to catheter-based renal sympathetic denervation in severe resistant hypertension: data from the Greek Renal Denervation Registry

C Tsioufis, A Ziakas, K Dimitriadis, P Davlouros… - Clinical Research in …, 2017 - Springer
Abstract Background/Introduction The efficacy of catheter-based renal sympathetic
denervation (RDN) in terms of blood pressure (BP) reduction has been questioned, while …

[HTML][HTML] Skin sodium content as a predictor of blood pressure response to renal denervation

M Guenes-Altan, A Schmid, D Kannenkeril… - Hypertension …, 2024 - nature.com
Patients with treatment resistant hypertension (TRH) are known to have elevated sodium
(Na) content in muscle and skin. Renal denervation (RDN) emerged as an adjacent …

Impact of renal denervation on tissue Na+ content in treatment-resistant hypertension

C Ott, C Kopp, A Dahlmann, A Schmid, P Linz… - Clinical Research in …, 2018 - Springer
Objectives Renal denervation (RDN) has been introduced for reducing blood pressure (BP)
in treatment-resistant hypertension (TRH). The precise mechanism how RDN exerts its BP …