Molecular and cellular mechanisms of tooth development, homeostasis and repair
T Yu, OD Klein - Development, 2020 - journals.biologists.com
The tooth provides an excellent system for deciphering the molecular mechanisms of
organogenesis, and has thus been of longstanding interest to developmental and stem cell …
organogenesis, and has thus been of longstanding interest to developmental and stem cell …
Intertwined signaling pathways governing tooth development: a give-and-take between canonical Wnt and Shh
F Hermans, L Hemeryck, I Lambrichts… - Frontiers in cell and …, 2021 - frontiersin.org
Teeth play essential roles in life. Their development relies on reciprocal interactions
between the ectoderm-derived dental epithelium and the underlying neural crest-originated …
between the ectoderm-derived dental epithelium and the underlying neural crest-originated …
Planar differential growth rates initiate precise fold positions in complex epithelia
M Tozluoǧlu, M Duda, NJ Kirkland, R Barrientos… - Developmental cell, 2019 - cell.com
Tissue folding is a fundamental process that shapes epithelia into complex 3D organs. The
initial positioning of folds is the foundation for the emergence of correct tissue morphology …
initial positioning of folds is the foundation for the emergence of correct tissue morphology …
Mechanobiological approaches to synthetic morphogenesis: learning by building
M Matejčić, X Trepat - Trends in Cell Biology, 2023 - cell.com
Tissue morphogenesis occurs in a complex physicochemical microenvironment with limited
experimental accessibility. This often prevents a clear identification of the processes that …
experimental accessibility. This often prevents a clear identification of the processes that …
Synthetic development: building mammalian multicellular structures with artificial genetic programs
Synthetic biology efforts began in simple single-cell systems, which were relatively easy to
manipulate genetically (Cameron et al., 2014). The field grew exponentially in the last two …
manipulate genetically (Cameron et al., 2014). The field grew exponentially in the last two …
Developmental influence on evolutionary rates and the origin of placental mammal tooth complexity
AMC Couzens, KE Sears… - Proceedings of the …, 2021 - National Acad Sciences
Development has often been viewed as a constraining force on morphological adaptation,
but its precise influence, especially on evolutionary rates, is poorly understood. Placental …
but its precise influence, especially on evolutionary rates, is poorly understood. Placental …
Early perturbation of Wnt signaling reveals patterning and invagination-evagination control points in molar tooth development
R Kim, T Yu, J Li, J Prochazka, A Sharir… - …, 2021 - journals.biologists.com
Tooth formation requires complex signaling interactions both within the oral epithelium and
between the epithelium and the underlying mesenchyme. Previous studies of the Wnt/β …
between the epithelium and the underlying mesenchyme. Previous studies of the Wnt/β …
FACEts of mechanical regulation in the morphogenesis of craniofacial structures
W Du, A Bhojwani, JK Hu - International Journal of Oral Science, 2021 - nature.com
During embryonic development, organs undergo distinct and programmed morphological
changes as they develop into their functional forms. While genetics and biochemical signals …
changes as they develop into their functional forms. While genetics and biochemical signals …
A shark-inspired general model of tooth morphogenesis unveils developmental asymmetries in phenotype transitions
Developmental complexity stemming from the dynamic interplay between genetic and
biomechanic factors canalizes the ways genotypes and phenotypes can change in …
biomechanic factors canalizes the ways genotypes and phenotypes can change in …
On the evolution and development of morphological complexity: A view from gene regulatory networks
How does morphological complexity evolve? This study suggests that the likelihood of
mutations increasing phenotypic complexity becomes smaller when the phenotype itself is …
mutations increasing phenotypic complexity becomes smaller when the phenotype itself is …