Neuroinflammation in Alzheimer's disease: current progress in molecular signaling and therapeutics

S Thakur, R Dhapola, P Sarma, B Medhi, DHK Reddy - Inflammation, 2023 - Springer
Alzheimer's disease, a neurodegenerative disease with amyloid beta accumulation as a
major hallmark, has become a dire global health concern as there is a lack of clear …

Neuroinflammation in Alzheimer's disease

IG Onyango, GV Jauregui, M Čarná, JP Bennett Jr… - Biomedicines, 2021 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disease associated with human aging.
Ten percent of individuals over 65 years have AD and its prevalence continues to rise with …

Increased risk of COVID‐19 infection and mortality in people with mental disorders: analysis from electronic health records in the United States

QQ Wang, R Xu, ND Volkow - World Psychiatry, 2021 - Wiley Online Library
Concerns have been expressed that persons with a pre‐existing mental disorder may
represent a population at increased risk for COVID‐19 infection and with a higher likelihood …

[HTML][HTML] COVID-19 risk and outcomes in patients with substance use disorders: analyses from electronic health records in the United States

QQ Wang, DC Kaelber, R Xu, ND Volkow - Molecular psychiatry, 2021 - nature.com
The global pandemic of COVID-19 is colliding with the epidemic of opioid use disorders
(OUD) and other substance use disorders (SUD) in the United States (US). Currently, there …

Analyses of risk, racial disparity, and outcomes among US patients with cancer and COVID-19 infection

QQ Wang, NA Berger, R Xu - JAMA oncology, 2021 - jamanetwork.com
Importance Patients with specific cancers may be at higher risk than those without cancer for
coronavirus disease 2019 (COVID-19) and its severe outcomes. At present, limited data are …

Overview of dual-acting drug methotrexate in different neurological diseases, autoimmune pathologies and cancers

P Koźmiński, PK Halik, R Chesori… - International journal of …, 2020 - mdpi.com
Methotrexate, a structural analogue of folic acid, is one of the most effective and extensively
used drugs for treating many kinds of cancer or severe and resistant forms of autoimmune …

Connecting aging biology and inflammation in the omics era

KA Walker, N Basisty, DM Wilson… - The Journal of Clinical …, 2022 - Am Soc Clin Investig
Aging is characterized by the accumulation of damage to macromolecules and cell
architecture that triggers a proinflammatory state in blood and solid tissues, termed …

Role of chronic neuroinflammation in neuroplasticity and cognitive function: A hypothesis

D Lecca, YJ Jung, MT Scerba, I Hwang… - Alzheimer's & …, 2022 - Wiley Online Library
Objective Evaluating the efficacy of 3, 6'‐dithioPomalidomide in 5xFAD Alzheimer's disease
(AD) mice to test the hypothesis that neuroinflammation is directly involved in the …

Psychological processes mediating the association between developmental trauma and specific psychotic symptoms in adults: A systematic review and meta‐analysis

MAP Bloomfield, T Chang, MJ Woodl… - World …, 2021 - Wiley Online Library
Experiencing psychological trauma during childhood and/or adolescence is associated with
an increased risk of psychosis in adulthood. However, we lack a clear knowledge of how …

Psoriasis and systemic inflammatory disorders

T Tashiro, Y Sawada - International journal of molecular sciences, 2022 - mdpi.com
Psoriasis is a representative inflammatory skin disease occupied by large surface
involvement. As inflammatory cells and cytokines can systemically circulate in various …