Portrait of a Pathogen: The Mycobacterium tuberculosis Proteome In Vivo
Background Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), is a
facultative intracellular pathogen that can persist within the host. The bacteria are thought to …
facultative intracellular pathogen that can persist within the host. The bacteria are thought to …
Detection of Mycobacterium tuberculosis Peptides in the Exosomes of Patients with Active and Latent M. tuberculosis Infection Using MRM-MS
NA Kruh-Garcia, LM Wolfe, LH Chaisson… - PloS one, 2014 - journals.plos.org
The identification of easily measured, accurate diagnostic biomarkers for active tuberculosis
(TB) will have a significant impact on global TB control efforts. Because of the host and …
(TB) will have a significant impact on global TB control efforts. Because of the host and …
Proteomic Definition of the Cell Wall of Mycobacterium tuberculosis
LM Wolfe, SB Mahaffey, NA Kruh… - Journal of proteome …, 2010 - ACS Publications
The cell envelope of Mycobacterium tuberculosis (Mtb) is complex and diverse; composed of
proteins intermingled in a matrix of peptidoglycan, mycolic acids, lipids, and carbohydrates …
proteins intermingled in a matrix of peptidoglycan, mycolic acids, lipids, and carbohydrates …
Upregulation of the Phthiocerol Dimycocerosate Biosynthetic Pathway by Rifampin-Resistant, rpoB Mutant Mycobacterium tuberculosis
Multidrug-resistant tuberculosis has emerged as a major threat to tuberculosis control.
Phylogenetically related rifampin-resistant actinomycetes with mutations mapping to …
Phylogenetically related rifampin-resistant actinomycetes with mutations mapping to …
Recent insights into Mycobacterium tuberculosis through proteomics and implications for the clinic
D Bisht, D Sharma, D Sharma, R Singh… - Expert Review of …, 2019 - Taylor & Francis
Introduction: This review aimed at providing an update on the application of proteomics-
based approaches to gain recent insights of Mycobacterium tuberculosis (M. tb) and its …
based approaches to gain recent insights of Mycobacterium tuberculosis (M. tb) and its …
Tuberculosis: global approaches to a global disease
DE Kirschner, D Young, JAL Flynn - Current opinion in biotechnology, 2010 - Elsevier
Mycobacterium tuberculosis is a remarkably successful human pathogen. The interaction
with the human host is complex and much remains unknown. Recent advances in systems …
with the human host is complex and much remains unknown. Recent advances in systems …
Modification of the head proteome of nurse honeybees (Apis mellifera) exposed to field-relevant doses of pesticides
Understanding the effect of pesticides on the survival of honeybee colonies is important
because these pollinators are reportedly declining globally. In the present study, we …
because these pollinators are reportedly declining globally. In the present study, we …
Second generation multiple reaction monitoring assays for enhanced detection of ultra-low abundance Mycobacterium tuberculosis peptides in human serum
Abstract Background Mycobacterium tuberculosis (Mtb) is the causative agent of
Tuberculosis (TB), the number one cause of death due to an infectious disease. TB …
Tuberculosis (TB), the number one cause of death due to an infectious disease. TB …
Characterization of the Mycobacterium tuberculosis Proteome by Liquid Chromatography Mass Spectrometry-based Proteomics Techniques: A Comprehensive …
C Bell, GT Smith, MJ Sweredoski… - Journal of proteome …, 2012 - ACS Publications
Approximately, one-third of the world's population is infected with Mycobacterium
tuberculosis, the causative agent of Tuberculosis. Secreted and membrane proteins that …
tuberculosis, the causative agent of Tuberculosis. Secreted and membrane proteins that …
Deciphering the proteome of the in vivo diagnostic reagent “purified protein derivative” from Mycobacterium tuberculosis
Purified protein derivative (PPD) has served as a safe and effective diagnostic reagent for 60
years and is the only broadly available material to diagnose latent tuberculosis infections …
years and is the only broadly available material to diagnose latent tuberculosis infections …