Hydrogels are crosslinked polymer chains with three-dimensional (3D) network structures,
which can absorb relatively large amounts of fluid. Because of the high water content, soft …

A number of stimuli-responsive-based hydrogels has been widely explored in biomedical
applications in the last few decades because of their excellent biodegradability and …

Gene therapy by expression constructs or down-regulation of certain genes has shown great
potential for the treatment of various diseases. The wide clinical application of nucleic acid …

Targeted delivery combined with controlled drug release has a pivotal role in the future of
personalized medicine. This review covers the principles, advantages, and drawbacks of …

The oral route is a popular and convenient means of drug delivery. However, despite its
advantages, it also has challenges. Many drugs are not suitable for oral delivery due to: first …

Ferroptosis is a novel form of programmed cell death impelled by iron-dependent lipid
peroxidation, which may be a potential strategy for cancer therapy. Here we demonstrated …

The administration of drugs, as a main challenge of pharmaceutical and medicinal
applications, has certainly benefited from the application of synthetic polymers. However …

Deep-eutectic solvents (DESs) are often considered to be safe, eco-friendly and non-toxic
solvents. Due to these green credentials, they are increasingly being studied for application …

Breast cancer is the most prevalent non-cutaneous malignancy in women, with greater than
a million new cases every year. In the last decennium, numerous diagnostic and treatment …

Among modern drug formulations, stimuli-responsive hydrogels also called “smart
hydrogels” deserve a special attention. The basic feature of this system is the ability to …