Exploring the Zika genome to design a potential multiepitope vaccine using an immunoinformatics approach

A Mittal, S Sasidharan, S Raj, SN Balaji… - International Journal of …, 2020 - Springer
Zika is one of the most dreaded viruses which has left mankind crippled for over years.
Current no vaccines for Zika are available in the market and only a few are in the clinical …

[HTML][HTML] An in silico reverse vaccinology approach to design a novel multiepitope peptide vaccine for non-small cell lung cancers

MM Rahman, MHU Masum, A Talukder… - Informatics in Medicine …, 2023 - Elsevier
Non-small cell lung cancer (NSCLC) is the most prevalent and fatal lung cancer. The
multiepitope vaccine is one of the immunotherapies successfully applied to treat NSCLC …

An mRNA vaccine for pancreatic cancer designed by applying in silico immunoinformatics and reverse vaccinology approaches

MHU Masum, S Wajed, MI Hossain, NR Moumi… - Plos one, 2024 - journals.plos.org
Pancreatic ductal adenocarcinoma is the most prevalent pancreatic cancer, which is
considered a significant global health concern. Chemotherapy and surgery are the …

In silico vaccine design against Chlamydia trachomatis infection

S Shiragannavar, S Madagi, J Hosakeri… - … Modeling Analysis in …, 2020 - Springer
Chlamydia trachomatis, a gram-negative bacterium known to infect the genital sites mainly
columnar epithelial cells of the cervix, urethra and rectum in women and causes acute …

[HTML][HTML] Designing of a multiepitope-based chimeric vaccine against dengue virus serotype 3 (DENV-3) through next generation reverse vaccinology approaches

MHU Masum, J Ferdous, S Lokman… - Informatics in Medicine …, 2024 - Elsevier
The dengue virus (DENV) causes dengue infection and has become a significant global
public health concern. The successful application of immunotherapies in treating dengue …

In silico design of a trivalent multi-epitope global-coverage vaccine-candidate protein against influenza viruses: evaluation by molecular dynamics and immune …

A Jalalvand, F Fotouhi, G Bahramali… - Journal of …, 2023 - Taylor & Francis
Hemagglutinin (HA), a variable viral surface protein, is essential for influenza vaccine
development. Annually, traditional trivalent vaccines containing influenza A/H1N1, A/H3N2 …

[HTML][HTML] Production of a Novel Multi-Epitope Peptide Vaccine against Hepatocellular Carcinoma

FM Dehbarez, S Mahmoodi - Iranian Journal of Medical Sciences, 2022 - ncbi.nlm.nih.gov
Background: Hepatocellular carcinoma (HCC) is one of the prevalent cancers in the world
with a high recurrence rate. In recent years, different researches have focused on designing …

Utilising capsid proteins of poliovirus to design a multi-epitope based subunit vaccine by immunoinformatics approach

N Bohra, S Sasidharan, S Raj, SN Balaji… - Molecular …, 2020 - Taylor & Francis
Current vaccines used for polio are live attenuated oral polio vaccine and inactivated polio
vaccine. Recently, in India, the relapse of virulence was observed in attenuated viruses …

Exploring PLAC1 structure and underlying mechanisms to design a derivative vaccine against breast Cancer progression; In-Silico Study

F Afzali, P Ghahremanifard, MM Ranjbar… - Current …, 2020 - ingentaconnect.com
Background: The tolerogenic homeostasis in Breast Cancer (BC) can be surpassed by
rationally designed immune-encouraging constructs against tumor-specific antigens through …

Immunopeptidome screening to design An immunogenic construct against PRAME positive breast cancer; An in silico study

F Afzali, Z Minuchehr, S Jahangiri… - Computational Biology and …, 2020 - Elsevier
Background Metastasis is the main cause of breast cancer (BC) lethality, especially in early
stages, led to improvements in therapeutic procedures. Lately, by improvements in our …