[HTML][HTML] Comorbidities, multimorbidity and COVID-19

CD Russell, NI Lone, JK Baillie - Nature medicine, 2023 - nature.com
The influence of comorbidities on COVID-19 outcomes has been recognized since the
earliest days of the pandemic. But establishing causality and determining underlying …

[HTML][HTML] Global and regional prevalence of multimorbidity in the adult population in community settings: a systematic review and meta-analysis

SR Chowdhury, DC Das, TC Sunna, J Beyene… - …, 2023 - thelancet.com
Background Knowing the prevalence of multimorbidity among adults across continents is a
crucial piece of information for achieving Sustainable Development Goal 3.4, which calls for …

Targeting cellular senescence with senotherapeutics: senolytics and senomorphics

L Zhang, LE Pitcher, V Prahalad… - The FEBS …, 2023 - Wiley Online Library
The concept of geroscience is that since ageing is the greatest risk factor for many diseases
and conditions, targeting the ageing process itself will have the greatest impact on human …

[HTML][HTML] Diretrizes brasileiras de hipertensão arterial–2020

WKS Barroso, CIS Rodrigues, LA Bortolotto… - Arquivos brasileiros de …, 2021 - SciELO Brasil
A hipertensão arterial (HA) é uma doença crônica não transmissível (DCNT) definida por
níveis pressóricos, em que os benefícios do tratamento (não medicamentoso e/ou …

Multimorbidity

ST Skou, FS Mair, M Fortin, B Guthrie… - Nature Reviews …, 2022 - nature.com
Multimorbidity (two or more coexisting conditions in an individual) is a growing global
challenge with substantial effects on individuals, carers and society. Multimorbidity occurs a …

An inflammatory aging clock (iAge) based on deep learning tracks multimorbidity, immunosenescence, frailty and cardiovascular aging

N Sayed, Y Huang, K Nguyen, Z Krejciova-Rajaniemi… - Nature aging, 2021 - nature.com
While many diseases of aging have been linked to the immunological system, immune
metrics capable of identifying the most at-risk individuals are lacking. From the blood …

Digital interventions for the treatment of depression: A meta-analytic review.

I Moshe, Y Terhorst, P Philippi, M Domhardt… - Psychological …, 2021 - psycnet.apa.org
The high global prevalence of depression, together with the recent acceleration of remote
care owing to the COVID-19 pandemic, has prompted increased interest in the efficacy of …

[HTML][HTML] Risk factors for Covid-19 severity and fatality: a structured literature review

D Wolff, S Nee, NS Hickey, M Marschollek - Infection, 2021 - Springer
Purpose Covid-19 is a global threat that pushes health care to its limits. Since there is
neither a vaccine nor a drug for Covid-19, people with an increased risk for severe and fatal …

[HTML][HTML] Brazilian guidelines of hypertension–2020

WKS Barroso, CIS Rodrigues, LA Bortolotto… - Arquivos brasileiros de …, 2021 - SciELO Brasil
SciELO - Brasil - Diretrizes Brasileiras de Hipertensão Arterial – 2020 Diretrizes Brasileiras de
Hipertensão Arterial – 2020 Acessibilidade / Reportar erro Brasil Lista alfabética de periódicos …

[HTML][HTML] Global, regional, and national estimates of the population at increased risk of severe COVID-19 due to underlying health conditions in 2020: a modelling study

A Clark, M Jit, C Warren-Gash, B Guthrie… - The Lancet Global …, 2020 - thelancet.com
Background The risk of severe COVID-19 if an individual becomes infected is known to be
higher in older individuals and those with underlying health conditions. Understanding the …