Simple Summary Biliary tract cancers (BTC) include gallbladder cancers, intrahepatic,
perihilar and distal extrahepatic cholangiocarcinomas. BTCs represent a major health …

PURPOSE Biliary tract cancers (BTCs) are aggressive cancers that carry a poor prognosis.
An enhanced understanding of the immune landscape of anatomically and molecularly …

Background The proto‐oncogene ROS1 encodes an intrinsic type I membrane protein of the
tyrosine kinase/insulin receptor family. ROS1 facilitates the progression of various …

Introduction Bile duct cancer (cholangiocarcinoma, CCA) has a poor prognosis for patients,
and despite recent advances in targeted therapies for other cancer types, it is still treated …

In this phase I, dose‐escalation study, we sought to determine the maximum tolerated dose
(MTD) of the anaplastic lymphoma kinase/c‐ROS oncogene 1 receptor (ALK/ROS1) inhibitor …

The technique 3'rapid amplification of cDNA ends (3′ RACE) allows for detection of
translocations with unknown gene partners located at the 3′ end of the chimeric transcript …

Background Cholangiocarcinoma (CCA) is a fatal cancer of the bile duct with a poor
prognosis owing to limited therapeutic options. The incidence of intrahepatic CCA (iCCA) is …

Аннотация Цель исследования–оценить частоту и клиническое значение различных
молекулярно-генетических нарушений при опухолях билиарного тракта и определить …