Recent Scientific Advancements towards a Vaccine against Group A Streptococcus

J Fan, I Toth, RJ Stephenson - Vaccines, 2024 - mdpi.com
Group A Streptococcus (GAS), or Streptococcus pyogenes, is a gram-positive bacterium that
extensively colonises within the human host. GAS is responsible for causing a range of …

Autoimmunity in acute poststreptococcal GN: a neglected aspect of the disease

B Rodriguez-Iturbe - Journal of the American Society of …, 2021 - journals.lww.com
Acute poststreptococcal GN (APSGN) is the prototype of immune complex GN and is
associated with manifestations of autoimmune reactivity that have been neglected as …

[HTML][HTML] Concerns for efficacy of a 30-valent M-protein-based Streptococcus pyogenes vaccine in regions with high rates of rheumatic heart disease

PM Giffard, SYC Tong, DC Holt, AP Ralph… - PLoS neglected …, 2019 - journals.plos.org
The prevalence of rheumatic heart disease (RHD) in the Aboriginal population of the
Australian Northern Territory is high, and Streptococcus pyogenes skin infections likely …

Renal Autoimmunity: The Role of Bacterial and Viral Infections–An Extensive Review

N Lavine, A Ohayon, N Mahroum - Infection and Autoimmunity, 2024 - Elsevier
Autoimmunity is a process by which the loss of self-tolerance results in an immune attack
against the body own tissues and organs. For autoimmunity to occur, various elements …

[HTML][HTML] Post-streptococcus pyogenes glomerulonephritis

B Rodriguez-Iturbe, M Haas - 2022 - europepmc.org
Acute glomerulonephritis that results from streptococcal infections is the best-studied
immune complex-mediated glomerulonephritis. Initially described in the convalescence of …

Infection-Related Glomerulonephritis in Children and Adults

A Iyengar, N Kamath, J Radhakrishnan… - Seminars in …, 2024 - Elsevier
Infection-related glomerulonephritis is an immunologically mediated glomerular injury after
an infection. Glomerulonephritis may occur with the infection or after a variable latent period …

[HTML][HTML] Using genomics to understand the epidemiology of infectious diseases in the Northern territory of Australia

EM Meumann, VL Krause, R Baird… - Tropical Medicine and …, 2022 - mdpi.com
The Northern Territory (NT) is a geographically remote region of northern and central
Australia. Approximately a third of the population are First Nations Australians, many of …

[HTML][HTML] The heterophilicic epitopes in conserved HA regions of human and avian influenza viruses can produce antibodies that bound to kidney tissue

C yan Guo, Z kui Jin, Q Feng, Y meng Feng… - Microbial …, 2023 - Elsevier
Influenza virus infection can cause kidney damage. However, the link between influenza
infection and disease is still unclear. The purpose of this study was to analyze the …

Sociodemographic determinants of chronic kidney disease in Indigenous children

A Dart - Pediatric Nephrology, 2022 - Springer
Rates of chronic kidney disease (CKD) are disproportionately increased in Indigenous
peoples. The focus has traditionally been on adults, as they experience the highest rates of …

Reduction in Acute Post-Streptococcal Glomerulonephritis Incidence in Counties Manukau, New Zealand, after the COVID-19 Pandemic.

A Taylor, J Neutze, NJ Moreland… - The American Journal of …, 2024 - europepmc.org
The COVID-19 pandemic has altered the epidemiology of many common childhood
infections, including Group A streptococcal (GAS) disease. Acute post-streptococcal …