A brief overview of global trends in MSC-based cell therapy
Human mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or
medicinal signaling cells, are important adult stem cells for regenerative medicine, largely …
medicinal signaling cells, are important adult stem cells for regenerative medicine, largely …
[HTML][HTML] Advances and challenges in stem cell culture
C McKee, GR Chaudhry - Colloids and surfaces B: Biointerfaces, 2017 - Elsevier
Stem cells (SCs) hold great promise for cell therapy, tissue engineering, and regenerative
medicine as well as pharmaceutical and biotechnological applications. They have the …
medicine as well as pharmaceutical and biotechnological applications. They have the …
Advances in biomaterial‐based spinal cord injury repair
Spinal cord injury (SCI) often leads to the loss of motor and sensory functions and is a major
challenge in neurological clinical practice. Understanding the pathophysiological changes …
challenge in neurological clinical practice. Understanding the pathophysiological changes …
Regeneration of spinal cord connectivity through stem cell transplantation and biomaterial scaffolds
H Katoh, K Yokota, MG Fehlings - Frontiers in cellular neuroscience, 2019 - frontiersin.org
Significant progress has been made in the treatment of spinal cord injury (SCI). Advances in
post-trauma management and intensive rehabilitation have significantly improved the …
post-trauma management and intensive rehabilitation have significantly improved the …
Inflammation-stimulated mesenchymal stromal cell-derived extracellular vesicles attenuate inflammation
Extracellular vesicles (EVs) secreted by mesenchymal stromal cells (MSCs) have been
proposed to be a key mechanistic link in the therapeutic efficacy of cells in response to …
proposed to be a key mechanistic link in the therapeutic efficacy of cells in response to …
Current concepts of biomaterial scaffolds and regenerative therapy for spinal cord injury
Spinal cord injury (SCI) is a catastrophic condition associated with significant neurological
deficit and social and financial burdens. It is currently being managed symptomatically, with …
deficit and social and financial burdens. It is currently being managed symptomatically, with …
Reduced graphene oxide‐encapsulated microfiber patterns enable controllable formation of neuronal‐like networks
Scaffold‐guided formation of neuronal‐like networks, especially under electrical stimulation,
can be an appealing avenue toward functional restoration of injured nervous systems. Here …
can be an appealing avenue toward functional restoration of injured nervous systems. Here …
Spinal cord repair: from cells and tissue engineering to extracellular vesicles
S Guo, I Redenski, S Levenberg - Cells, 2021 - mdpi.com
Spinal cord injury (SCI) is a debilitating condition, often leading to severe motor, sensory, or
autonomic nervous dysfunction. As the holy grail of regenerative medicine, promoting spinal …
autonomic nervous dysfunction. As the holy grail of regenerative medicine, promoting spinal …
Roles of mesenchymal stem cells in spinal cord injury
J Qu, H Zhang - Stem cells international, 2017 - Wiley Online Library
Spinal cord injury (SCI) represents one of the most complicated and heterogeneous
pathological processes of central nervous system (CNS) impairments, which is still beyond …
pathological processes of central nervous system (CNS) impairments, which is still beyond …
Regenerating the injured spinal cord at the chronic phase by engineered iPSCs‐derived 3D neuronal networks
L Wertheim, R Edri, Y Goldshmit, T Kagan… - Advanced …, 2022 - Wiley Online Library
Cell therapy using induced pluripotent stem cell‐derived neurons is considered a promising
approach to regenerate the injured spinal cord (SC). However, the scar formed at the …
approach to regenerate the injured spinal cord (SC). However, the scar formed at the …