A brief overview of global trends in MSC-based cell therapy

D Jovic, Y Yu, D Wang, K Wang, H Li, F Xu… - Stem cell reviews and …, 2022 - Springer
Human mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or
medicinal signaling cells, are important adult stem cells for regenerative medicine, largely …

[HTML][HTML] Advances and challenges in stem cell culture

C McKee, GR Chaudhry - Colloids and surfaces B: Biointerfaces, 2017 - Elsevier
Stem cells (SCs) hold great promise for cell therapy, tissue engineering, and regenerative
medicine as well as pharmaceutical and biotechnological applications. They have the …

Advances in biomaterial‐based spinal cord injury repair

H Shen, C Fan, Z You, Z Xiao… - Advanced Functional …, 2022 - Wiley Online Library
Spinal cord injury (SCI) often leads to the loss of motor and sensory functions and is a major
challenge in neurological clinical practice. Understanding the pathophysiological changes …

Regeneration of spinal cord connectivity through stem cell transplantation and biomaterial scaffolds

H Katoh, K Yokota, MG Fehlings - Frontiers in cellular neuroscience, 2019 - frontiersin.org
Significant progress has been made in the treatment of spinal cord injury (SCI). Advances in
post-trauma management and intensive rehabilitation have significantly improved the …

Inflammation-stimulated mesenchymal stromal cell-derived extracellular vesicles attenuate inflammation

MT Harting, AK Srivastava, S Zhaorigetu, H Bair… - Stem …, 2018 - academic.oup.com
Extracellular vesicles (EVs) secreted by mesenchymal stromal cells (MSCs) have been
proposed to be a key mechanistic link in the therapeutic efficacy of cells in response to …

Current concepts of biomaterial scaffolds and regenerative therapy for spinal cord injury

H Suzuki, Y Imajo, M Funaba, H Ikeda… - International Journal of …, 2023 - mdpi.com
Spinal cord injury (SCI) is a catastrophic condition associated with significant neurological
deficit and social and financial burdens. It is currently being managed symptomatically, with …

Reduced graphene oxide‐encapsulated microfiber patterns enable controllable formation of neuronal‐like networks

J Wang, H Wang, X Mo, H Wang - Advanced Materials, 2020 - Wiley Online Library
Scaffold‐guided formation of neuronal‐like networks, especially under electrical stimulation,
can be an appealing avenue toward functional restoration of injured nervous systems. Here …

Spinal cord repair: from cells and tissue engineering to extracellular vesicles

S Guo, I Redenski, S Levenberg - Cells, 2021 - mdpi.com
Spinal cord injury (SCI) is a debilitating condition, often leading to severe motor, sensory, or
autonomic nervous dysfunction. As the holy grail of regenerative medicine, promoting spinal …

Roles of mesenchymal stem cells in spinal cord injury

J Qu, H Zhang - Stem cells international, 2017 - Wiley Online Library
Spinal cord injury (SCI) represents one of the most complicated and heterogeneous
pathological processes of central nervous system (CNS) impairments, which is still beyond …

Regenerating the injured spinal cord at the chronic phase by engineered iPSCs‐derived 3D neuronal networks

L Wertheim, R Edri, Y Goldshmit, T Kagan… - Advanced …, 2022 - Wiley Online Library
Cell therapy using induced pluripotent stem cell‐derived neurons is considered a promising
approach to regenerate the injured spinal cord (SC). However, the scar formed at the …