Hypertrophic cardiomyopathy (HCM) is a highly treatable monogenetic disorder affecting
nearly 0.2% of the population. The high burden of this disease demands suitable measures …

Transcatheter electrosurgery describes the ability to cut and traverse tissue, at a distance,
without an open surgical field and is possible using either purpose-built or off-the-shelf …

Background Left ventricular outflow tract (LVOT) obstruction is a source of morbidity in
hypertrophic cardiomyopathy (HCM) and a life-threatening complication of transcatheter …

Pathologic left ventricular remodeling and valvular heart disease may contribute to the
clinical presentation and outcomes of patients presenting with heart failure, and limit the …

Background Deep intramural ventricular tachycardia substrate targets are difficult to access,
map, and ablate from endocardial and epicardial surfaces, resulting in high recurrence …

OBJECTIVES Ring annuloplasty represents the standard surgical treatment, but offers
suboptimal results in patients with severe functional tricuspid regurgitation. Addition of …

Cardiovascular disease is the most common cause of death worldwide, resulting in millions
of deaths annually. Currently, there are still some deficiencies in the treatment of …

Left ventricular (LV) mass, geometry, and architecture are prone to change in response to
neurohormonal activation and physical stresses on the myocytes—a process termed …

Aims Pressure–volume (PV) loops have utility in the evaluation of cardiac pathophysiology
but require invasive measurements. Recently, a time-varying elastance model to derive PV …

Chronic heart failure (HF) is a clinical syndrome of myocardial dysfunction characterized by
inadequate cardiac output or preserved output that can only be achieved by sustaining …