Drosophila visual transduction is the fastest known G-protein-coupled signaling cascade
and has therefore served as a genetically tractable animal model for characterizing rapid …

Based on the molecular structure of the individual members of the protein kinase C family,
general properties and the mode of activation of this enzyme family are discussed …

Phytochrome is a plant regulatory photoreceptor that mediates red light effects on a wide
variety of physiological and molecular responses. DNA blot analysis indicates that the …

NEUROTRANSMITTERS are released at synapses by the Ca2+-regulated exocytosis of
synaptic vesicles, which are specialized secretory organelles that store high concentrations …

The establishment and maintenance of polarity is of fundamental importance for the function
of epithelial and neuronal cells. In Drosophila, the multi-PDZ domain protein Bazooka (Baz) …

Abstract Background: Protein kinase Cs are a family of enzymes that transduce the plethora
of signals promoting lipid hydrolysis. Here, we show that protein kinase C must first be …

The immunosuppressive agent rapamycin induces inactivation of p70s6k with no effect on
other mitogen‐activated kinases. Here we have employed a combination of techniques …

The Drosophila auditory organ shares equivalent transduction mechanisms with vertebrate
hair cells, and both are specified by atonal family genes. Using a whole-organ knockout …

RECENT evidence suggests that the force for poleward movement of chromosomes during
mitosis is generated at or close to the kinetochores1, 2. Chromosome movement depends …

Probes derived from cDNAs encoding isozymes of rat protein kinase C (PKC) were used to
screen the genome of the budding yeast S. cerevisiae. A single gene (PKCI) was isolated …