Molecular pathways linking adipose innervation to insulin action in obesity and diabetes mellitus

A Guilherme, F Henriques, AH Bedard… - Nature Reviews …, 2019 - nature.com
Adipose tissue comprises adipocytes and many other cell types that engage in dynamic
crosstalk in a highly innervated and vascularized tissue matrix. Although adipose tissue has …

Impact of the autonomic nervous system on the skeleton

F Elefteriou - Physiological reviews, 2018 - journals.physiology.org
It is from the discovery of leptin and the central nervous system as a regulator of bone
remodeling that the presence of autonomic nerves within the skeleton transitioned from a …

[HTML][HTML] Perirenal adipose tissue inflammation: novel insights linking metabolic dysfunction to renal diseases

SH Hammoud, I AlZaim, Y Al-Dhaheri, AH Eid… - Frontiers in …, 2021 - frontiersin.org
A healthy adipose tissue (AT) is indispensable to human wellbeing. Among other roles, it
contributes to energy homeostasis and provides insulation for internal organs. Adipocytes …

Response to immune checkpoint blockade improved in pre-clinical model of breast cancer after bariatric surgery

LM Sipe, M Chaib, EB Korba, H Jo, MC Lovely… - Elife, 2022 - elifesciences.org
Bariatric surgery is a sustainable weight loss approach, including vertical sleeve
gastrectomy (VSG). Obesity exacerbates tumor growth, while diet-induced weight loss …

[HTML][HTML] High-intensity interval training improves fatty infiltration in the rotator cuff through the β3 adrenergic receptor in mice

H Zhou, C Chen, H Hu, B Jiang, Y Yin… - Bone & Joint …, 2023 - boneandjoint.org.uk
Aims Rotator cuff muscle atrophy and fatty infiltration affect the clinical outcomes of rotator
cuff tear patients. However, there is no effective treatment for fatty infiltration at this time. High …

Neurobiology, stem cell biology, and immunology: an emerging triad for understanding tissue homeostasis and repair

E Scott-Solomon, YC Hsu - Annual review of cell and …, 2022 - annualreviews.org
The peripheral nervous system (PNS) endows animals with the remarkable ability to sense
and respond to a dynamic world. Emerging evidence shows the PNS also participates in …

[HTML][HTML] Age-dependent changes of adipokine and cytokine secretion from rat adipose tissue by endogenous and exogenous toll-like receptor agonists

V Peek, E Neumann, T Inoue, S Koenig… - Frontiers in …, 2020 - frontiersin.org
White adipose tissue but recently also brown adipose tissue have emerged as endocrine
organs. Age-associated obesity is accompanied by prolonged and elevated …

The effect of serum from calorie-restricted mouse on mTOR signaling in C2C12 myotubes

T Shirai, T Iwata, K Uemichi, R Tanimura… - Journal of …, 2023 - joe.bioscientifica.com
Graphical abstract Abstract Calorie restriction (CR) is a widely recognized dietary approach
with beneficial impacts on the entire body, including enhancements in oxidative metabolism …

[HTML][HTML] Impact of baseline adipose tissue characteristics on change in adipose tissue volume during a low calorie diet in people with obesity—results from the LION …

D Junker, M Wu, A Reik, J Raspe, S Rupp… - International Journal of …, 2024 - nature.com
Abstract Background/Objectives Weight loss outcomes vary individually. Magnetic
resonance imaging (MRI)-based evaluation of adipose tissue (AT) might help to identify AT …

Obesity-induced sympathoexcitation is associated with Nrf2 dysfunction in the rostral ventrolateral medulla

P Balasubramanian… - American Journal …, 2020 - journals.physiology.org
Increases in sympathetic nerve activity (SNA) have been implicated in obesity-induced risk
for cardiovascular diseases, especially hypertension. Previous studies indicate that …