Horizontally transferred genetic elements and their role in pathogenesis of bacterial disease

C Gyles, P Boerlin - Veterinary pathology, 2014 - journals.sagepub.com
This article reviews the roles that laterally transferred genes (LTG) play in the virulence of
bacterial pathogens. The features of LTG that allow them to be recognized in bacterial …

Shiga toxins and stx phages: highly diverse entities

A Krüger, PMA Lucchesi - Microbiology, 2015 - microbiologyresearch.org
Shiga toxins are the main virulence factors of a group of Escherichia coli strains [Shiga toxin-
producing E. coli (STEC)] that cause severe human diseases, such as haemorrhagic colitis …

Underlying mechanism of antimicrobial activity of chitosan microparticles and implications for the treatment of infectious diseases

SJ Jeon, M Oh, WS Yeo, KN Galvao, KC Jeong - PLoS One, 2014 - journals.plos.org
The emergence of antibiotic resistant microorganisms is a great public health concern and
has triggered an urgent need to develop alternative antibiotics. Chitosan microparticles …

Shiga toxin sub-type 2a increases the efficiency of Escherichia coli O157 transmission between animals and restricts epithelial regeneration in bovine enteroids

SF Fitzgerald, AE Beckett, J Palarea-Albaladejo… - PLoS …, 2019 - journals.plos.org
Specific Escherichia coli isolates lysogenised with prophages that express Shiga toxin (Stx)
can be a threat to human health, with cattle being an important natural reservoir. In many …

Influence of Season and Feedlot Location on Prevalence and Virulence Factors of Seven Serogroups of Escherichia coli in Feces of Western-Canadian Slaughter …

K Stanford, RP Johnson, TW Alexander, TA McAllister… - PLoS …, 2016 - journals.plos.org
Pooled feces collected over two years from 1749 transport trailers hauling western-
Canadian slaughter cattle were analysed by PCR for detection of Escherichia coli …

Evolution of a zoonotic pathogen: investigating prophage diversity in enterohaemorrhagic Escherichia coli O157 by long-read sequencing

S Shaaban, LA Cowley, SP McAteer… - Microbial …, 2016 - microbiologyresearch.org
Enterohaemorrhagic Escherichia coli (EHEC) O157 is a zoonotic pathogen for which
colonization of cattle and virulence in humans is associated with multiple horizontally …

Colonization of Beef Cattle by Shiga Toxin-Producing Escherichia coli during the First Year of Life: A Cohort Study

RA Mir, TA Weppelmann, M Elzo, S Ahn, JD Driver… - PLoS …, 2016 - journals.plos.org
Each year Shiga toxin-producing Escherichia coli (STEC) are responsible for 2.8 million
acute illnesses around the world and> 250,000 cases in the US. Lowering the prevalence of …

Comparative Pathogenomics of Escherichia coli: Polyvalent Vaccine Target Identification through Virulome Analysis

JR Clark, AM Maresso - Infection and Immunity, 2021 - Am Soc Microbiol
Comparative genomics of bacterial pathogens has been useful for revealing potential
virulence factors. Escherichia coli is a significant cause of human morbidity and mortality …

Genomic comparison reveals natural occurrence of clinically relevant multidrug-resistant extended-spectrum-β-lactamase-producing Escherichia coli strains

L Teng, S Lee, A Ginn, SM Markland… - Applied and …, 2019 - Am Soc Microbiol
The effectiveness of antibiotics has been challenged by the increasing frequency of
antimicrobial resistance (AMR), which has emerged as a major threat to global health …

British Escherichia coli O157 in Cattle Study (BECS): to determine the prevalence of E. coli O157 in herds with cattle destined for the food chain

MK Henry, SC Tongue, J Evans, C Webster… - Epidemiology & …, 2017 - cambridge.org
Escherichia coli O157 are zoonotic bacteria for which cattle are an important reservoir.
Prevalence estimates for E. coli O157 in British cattle for human consumption are over 10 …