Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest types of cancer. The
worldwide estimates of its incidence and mortality in the general population are eight cases …

The efficacy of nonsteroidal anti‐inflammatory drugs (NSAIDs) against inflammation, pain,
and fever has been supporting their worldwide use in the treatment of painful conditions and …

Background NLRP3 inflammasome acts as a danger signal sensor that triggers and
coordinates the inflammatory response. However, the roles of NLRP3 inflammasome in the …

Simple Summary PDAC is one of the most malignant tumors and its treatment, whether
surgery or chemotherapy, has shown poor results. Resistance to gemcitabine and other …

Pancreatic ductal adenocarcinoma is one of the deadliest cancers worldwide and the fourth
leading cause of cancer-related deaths in United States. Regardless of the advances in …

Tuft cells are epithelial chemosensory cells with unique morphological and molecular
characteristics, the most noticeable of which is a tuft of long and thick microvilli on their …

Despite advances in understanding of ovarian cancer biology, the progress in translation of
research findings into new therapies is still slow. It is associated in part with limitations of …

Doublecortin like kinase protein 1 (Dclk1) is a microtubule-associated protein with C-
terminal serine/threonine kinase domain. Originally designated Doublecortin and CaM …

The role of the unique T‐cell population, natural killer T (NKT) cells, which have similar
functions to NK cells in pancreatic cancer (PC), is not yet evaluated. To address the …

Investigating existing drugs for repositioning can enable overcoming bottlenecks in the drug
development process. Here, we investigated the effect and molecular mechanism of the …