Molecular switches of the ADP-ribosylation factor (ARF) GTPase family coordinate
intracellular trafficking at all sorting stations along the secretory pathway, from the ER-Golgi …

Nitrogen is one of the most important essential nutrient sources for biogenic activities.
Regulation of nitrogen metabolism in microorganisms is complicated and elaborate. For this …

ADP-ribosylation factor (ARF) GTPases are major regulators of cellular membrane
homeostasis. High sequence similarity and multiple, possibly redundant functions of the five …

Abstract Treatment of cells with brefeldin A (BFA) blocks secretory vesicle transport and
causes a collapse of the Golgi apparatus. To gain more insight into the cellular mechanisms …

Vesicle biogenesis, trafficking and signaling via Endoplasmic reticulum-Golgi network
support essential developmental processes and their disruption lead to neurodevelopmental …

ADP-ribosylation factors (Arfs) are small GTPases regulating membrane traffic in the
secretory pathway. They are closely related and appear to have overlapping functions …

Small GTPases of the ADP-ribosylation factor (ARF) family, except for ARF6, mainly localize
to the Golgi apparatus, where they trigger formation of coated carrier vesicles. We recently …

The actin cytoskeleton regulates many important cellular processes in the brain, including
cell division and proliferation, migration, and cytokinesis and differentiation. These …

Three Sec7 guanine nucleotide exchange factors (GEFs) activate ADP-ribosylation factors
(ARFs) to facilitate coating of transport vesicles within the secretory and endosomal …

CC chemokine receptor 2 (CCR2) is a dual-function receptor. Similar to other G protein–
coupled chemokine receptors, it promotes monocyte infiltration into tissues in response to …