Epidemiology of β-lactamase-producing pathogens

K Bush, PA Bradford - Clinical microbiology reviews, 2020 - Am Soc Microbiol
SUMMARY β-Lactam antibiotics have been widely used as therapeutic agents for the past
70 years, resulting in emergence of an abundance of β-lactam-inactivating β-lactamases …

Pseudomonas Aeruginosa: Arsenal of Resistance Mechanisms, Decades of Changing Resistance Profiles, and Future Antimicrobial Therapies

ME El Zowalaty, AA Al Thani, TJ Webster… - Future …, 2015 - Taylor & Francis
Antimicrobial resistance is one of the most serious public health issues facing humans since
the discovery of antimicrobial agents. The frequent, prolonged, and uncontrolled use of …

Epidemiology of common resistant bacterial pathogens in the countries of the Arab League

RA Moghnieh, ZA Kanafani, HZ Tabaja… - The lancet infectious …, 2018 - thelancet.com
No uniformly organised collection of data regarding antimicrobial resistance has occurred in
the countries of the Arab League. 19 countries of the Arab League have published data for …

β-Lactamase production in key gram-negative pathogen isolates from the Arabian Peninsula

HM Zowawi, HH Balkhy, TR Walsh… - Clinical microbiology …, 2013 - Am Soc Microbiol
Infections due to Gram-negative bacilli (GNB) are a leading cause of morbidity and mortality
worldwide. The extent of antibiotic resistance in GNB in countries of the Gulf Cooperation …

[HTML][HTML] Understanding the epidemiology of multi-drug resistant gram-negative bacilli in the Middle East using a one health approach

I Dandachi, A Chaddad, J Hanna, J Matta… - Frontiers in …, 2019 - frontiersin.org
In the last decade, extended-spectrum cephalosporin and carbapenem resistant Gram-
negative bacilli (GNB) have been extensively reported in the literature as being …

Antimicrobial Resistance Pattern and Their Beta‐Lactamase Encoding Genes among Pseudomonas aeruginosa Strains Isolated from Cancer Patients

MM Zafer, MH Al-Agamy… - BioMed research …, 2014 - Wiley Online Library
This study was designed to investigate the prevalence of metallo‐β‐lactamases (MBL) and
extended‐spectrum β‐lactamases (ESBL) in P. aeruginosa isolates collected from two …

Activity of imipenem/relebactam against Pseudomonas aeruginosa producing ESBLs and carbapenemases

S Mushtaq, D Meunier, A Vickers… - Journal of …, 2021 - academic.oup.com
Background ESBL-and carbapenemase-producing Pseudomonas aeruginosa are prevalent
in, for example, the Middle East, Eastern Europe and Latin America, though rarer elsewhere …

Molecular characterization of carbapenemase production among gram-negative bacteria in Saudi Arabia

ZA Memish, A Assiri, M Almasri, H Roshdy… - Microbial Drug …, 2015 - liebertpub.com
We characterized the molecular basis of carbapenemase production in carbapenem-
resistant Gram-negative bacteria isolated from hospitalized patients from Saudi Arabia in the …

[HTML][HTML] Genomic Characterization of Carbapenem-Non-susceptible Pseudomonas aeruginosa Clinical Isolates From Saudi Arabia Revealed a Global Dissemination …

M Doumith, S Alhassinah, A Alswaji, M Alzayer… - Frontiers in …, 2022 - frontiersin.org
Carbapenem-resistant P. aeruginosa has become a major clinical problem due to limited
treatment options. However, studies assessing the trends in the molecular epidemiology and …

[HTML][HTML] Detection of bla (IMP) and bla (VIM) metallo-β-lactamases genes among Pseudomonas aeruginosa strains

F Fallah, RS Borhan, A Hashemi - International journal of burns and …, 2013 - ncbi.nlm.nih.gov
Abstract Acquired Metallo-β-Lactamases (MBLs) are emerging resistance determinants in
Pseudomonas aeruginosa and other gram-negative bacteria. Using Combination Disk …