Epigenetics of pregnancy: looking beyond the DNA code

D Zuccarello, U Sorrentino, V Brasson, L Marin… - Journal of assisted …, 2022 - Springer
Epigenetics is the branch of genetics that studies the different mechanisms that influence
gene expression without direct modification of the DNA sequence. An ever-increasing …

The importance of non-coding RNAs in environmental stress-related developmental brain disorders: A systematic review of evidence associated with exposure to …

T Arzua, C Jiang, Y Yan, X Bai - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Brain development is a dynamic and lengthy process that includes cell proliferation,
migration, neurogenesis, gliogenesis, synaptogenesis, and pruning. Disruption of any of …

Gestational alcohol exposure altered DNA methylation status in the developing fetus

C Mandal, D Halder, KH Jung, YG Chai - International journal of …, 2017 - mdpi.com
Ethanol is well known as a teratogenic factor that is capable of inducing a wide range of
developmental abnormalities if the developing fetus is exposed to it. Duration and dose are …

[HTML][HTML] In utero alcohol exposure and the alteration of histone marks in the developing fetus: an epigenetic phenomenon of maternal drinking

C Mandal, D Halder, KH Jung… - International Journal of …, 2017 - ncbi.nlm.nih.gov
Ethanol is well known for its teratogenic effects during fetal development. Maternal alcohol
consumption allows the developing fetus to experience the detrimental effects of alcohol …

Maternal alcohol consumption and altered miRNAs in the developing fetus: Context and future perspectives

C Mandal, D Halder, KH Jung… - Journal of Applied …, 2018 - Wiley Online Library
Alcohol is a teratogenic agent that can cause a wide range of developmental disorders, and
sometimes, the effects persist throughout an individual's lifetime. Researchers have shown …

Bioinformatic analysis predicts that ethanol exposure during early development causes alternative splicing alterations of genes involved in RNA post-transcriptional …

C Fuentes-Beals, M Olivares-Costa, ME Andrés… - Plos one, 2023 - journals.plos.org
Prenatal ethanol exposure is associated with neurodevelopmental defects and long-lasting
cognitive deficits, which are grouped as fetal alcohol spectrum disorders (FASD). The …

[HTML][HTML] GSK-J4-mediated transcriptomic alterations in differentiating embryoid bodies

C Mandal, SH Kim, SC Kang, JC Chai, YS Lee… - Molecules and cells, 2017 - Elsevier
Histone-modifying enzymes are key players in the field of cellular differentiation. Here, we
used GSK-J4 to profile important target genes that are responsible for neural differentiation …

Dissemination of prenatal drinking guidelines: a preliminary study examining personal alcohol use among midwives in a southwestern US state

OA Olusanya, AE Barry - Journal of Midwifery & Women's …, 2020 - Wiley Online Library
Introduction The constellation of birth defects seen in fetuses exposed to alcohol in utero
have been described as fetal alcohol spectrum disorders. Evidence suggests that health …

[图书][B] Fetal alcohol spectrum disorders: Knowledge synthesis

S Roozen, G Kok, L Curfs - 2017 - cris.maastrichtuniversity.nl
This report describes current knowledge and gaps in knowledge regarding FASD in the
Netherlands. The steps of Intervention Mapping (IM) are used as a framework for analyzing …

Gene expression signatures after ethanol exposure in differentiating embryoid bodies

C Mandal, SH Kim, JC Chai, YS Lee, KH Jung… - Toxicology in Vitro, 2018 - Elsevier
During the differentiation process, various epigenetic factors regulate the precise expression
of important genes and control cellular fate. During this stage, the differentiating cells …