Single-stranded RNA molecules fold into extraordinarily complicated secondary and tertiary
structures as a result of intramolecular base pairing. In vivo, these RNA structures are not …

Deciphering the folding pathways and predicting the structures of complex three-
dimensional biomolecules is central to elucidating biological function. RNA is single …

Proper gene expression is essential for the survival of every cell. Once thought to be a
passive transporter of genetic information, RNA has recently emerged as a key player in …

RNA secondary structures have proven essential for understanding the regulatory functions
performed by RNA such as microRNAs, bacterial small RNAs, or riboswitches. This success …

Abstract Structure-seq is a high-throughput and quantitative method that provides genome-
wide information on RNA structure at single-nucleotide resolution. Structure-seq can be …

RNA serves many functions in biology such as splicing, temperature sensing, and innate
immunity. These functions are often determined by the structure of RNA. There is thus a …

RNA structure regulates bacterial gene expression by several distinct mechanisms via
environmental and cellular stimuli, one of which is temperature. While some genome-wide …

RNA molecules are important players in all domains of life and the study of the relationship
between their multiple flexible states and the associated biological roles has increased in …

How organisms perceive and respond to their surroundings is one of the great questions in
biology. It is clear that RNA plays key roles in sensing. Cellular and environmental cues that …

RNA is one of the most fascinating biomolecules in living systems given its structural
versatility to fold into elaborate architectures for important biological functions such as gene …