Sepsis—which is a severe life-threatening infection with organ dysfunction—initiates a
complex interplay of host pro-inflammatory and anti-inflammatory processes. Sepsis can be …

Critical illness polyneuropathies (CIP) and myopathies (CIM) are common complications of
critical illness. Several weakness syndromes are summarized under the term intensive care …

Sepsis is characterized by a systemic inflammatory response followed by
immunosuppression of the host. Metabolic defects and mitochondrial failure are common in …

Background Over the last few years, accumulating data have implicated a role for ferritin as
a signaling molecule and direct mediator of the immune system. Hyperferritinemia is …

Both quality improvement and clinical research efforts over the past few decades have
focused on consensus definition of sepsis and acute respiratory distress syndrome (ARDS) …

Sepsis is among the most common causes of death in hospitals. It arises from the host
response to infection. Currently, diagnosis relies on nonspecific physiological criteria and …

Severe acute kidney injury (AKI), especially when caused or accompanied by sepsis, is
associated with prolonged hospitalization, progression to chronic kidney disease (CKD) …

Sepsis is the leading cause of death in critically ill patients in the United States. Yet the
individual host response to septicemia is variable, depending on the patient's immune …

This paper reports on the consensus conference on the management of intra-abdominal
infections (IAIs) which was held on July 23, 2016, in Dublin, Ireland, as a part of the annual …

Background: Sepsis is a deadly immunological disorder and its pathophysiology is still
poorly understood. We aimed to determine if specific pro-inflammatory and anti-inflammatory …