[HTML][HTML] Reliability of common mouse behavioural tests of anxiety: A systematic review and meta-analysis on the effects of anxiolytics

M Rosso, R Wirz, AV Loretan, NA Sutter… - Neuroscience & …, 2022 - Elsevier
The validity of widely used rodent behavioural tests of anxiety has been questioned, as they
often fail to produce consistent results across independent replicate studies. In this study, we …

Review on mechanisms and interactions in concomitant use of herbs and warfarin therapy

PM Leite, MAP Martins, RO Castilho - Biomedicine & Pharmacotherapy, 2016 - Elsevier
The effectiveness of warfarin, an oral anticoagulant originally derived from a plant, is
strongly affected by patient's characteristics such as the age, presence of comorbidities, and …

Natural antioxidants of the underutilized and neglected plant species of Asia and South America

MH Shahrajabian, DJ Marmitt… - Letters in Drug Design …, 2023 - ingentaconnect.com
Background: Plants have played an essential role in the search for new compounds for the
most diverse therapeutic purposes. Recently, more attention has been paid to natural …

[HTML][HTML] Plants and phytochemicals potentials in tackling anxiety: a systematic review

N Phootha, N Yongparnichkul, Z Fang, RY Gan… - Phytomedicine Plus, 2022 - Elsevier
Background Anxiety is one of the psychiatric disorders that disturbs routine life including
moods and motivation. Excessive anxiety causes mental illnesses or anxiety disorders …

[HTML][HTML] Ent-kaurenoic acid-enriched Mikania glomerata leaves-complexed β-cyclodextrin: Pharmaceutical development and in vivo antitumor activity in a sarcoma …

AVF Alves, CR Melo, JL Chagas-Neto… - International Journal of …, 2023 - Elsevier
The extract obtained from Mikania glomerata leaves rich in ent-kaurenoic acid (ERKA)
shows cytotoxic activity in vitro, but its hydrophobic nature and thermosensitivity are issues …

[HTML][HTML] Identification of potential targets of cinnamon for treatment against Alzheimer's disease-related GABAergic synaptic dysfunction using network pharmacology

D Qian, Q Wang, S Lin, Y Li, X Gu, C Xia, Y Xu… - Scientific Reports, 2022 - nature.com
Cinnamon aqueous extract's active substance base remains unclear and its mechanisms,
mainly the therapeutic target of anti-Alzheimer's disease (AD)-related GABAergic synaptic …

Involvement of GABAergic, glutamatergic, opioidergic, and brain-derived neurotrophic factor systems in the trigeminal neuropathic pain process

F Finamor, VL Scarabelot, LF Medeiros, DJ Stein… - Neuroscience …, 2023 - Elsevier
Trigeminal neuropathic pain (TNP) is an intense pain condition characterized by
hyperalgesia and allodynia; however, its neural mechanisms are not completely understood …

Mikania glomerata Sprengel extract and its major compound ent-kaurenoic acid display activity against bacteria present in endodontic infections

DLC Moreti, LF Leandro, T da Silva Moraes… - Anaerobe, 2017 - Elsevier
The search for new, effective and safe antimicrobial compounds from plant sources has
continued to play an important role in the maintenance of human health since ancient times …

Anxiolytic effect of fatty acids and terpenes fraction from Aloysia triphylla: Serotoninergic, GABAergic and glutamatergic implications

E Jiménez-Ferrer, MA Santillán-Urquiza… - Biomedicine & …, 2017 - Elsevier
Aloysia triphylla (Verbenaceae) is an aromatic medicinal plant, and it is used for the
treatment of “nervous” problems as,“sadness” and “nervousness”. While, there are no …

Essential oils as alternative promising anti-candidal agents: Progress and prospects

A Shala, S Singh, S Hameed… - Current Pharmaceutical …, 2022 - ingentaconnect.com
Candida albicans is one of the main agents responsible for opportunistic pathogenic
infections. The progressive emergence of fungal resistance to conventional antibiotics and …