Imaging of anticancer drug action in single cells
MA Miller, R Weissleder - Nature Reviews Cancer, 2017 - nature.com
Imaging is widely used in anticancer drug development, typically for whole-body tracking of
labelled drugs to different organs or to assess drug efficacy through volumetric …
labelled drugs to different organs or to assess drug efficacy through volumetric …
Recording the wild lives of immune cells
Intravital microscopic imaging can uncover fundamental aspects of immune cell behavior in
real time in both healthy and pathological states. Here, we discuss approaches for single …
real time in both healthy and pathological states. Here, we discuss approaches for single …
Cancer cell membrane-biomimetic nanoprobes with two-photon excitation and near-infrared emission for intravital tumor fluorescence imaging
Y Lv, M Liu, Y Zhang, X Wang, F Zhang, F Li, WE Bao… - ACS …, 2018 - ACS Publications
Biomimetic fluorescent nanoprobes capable of emitting near-infrared (NIR) fluorescence
(λmax≈ 720 nm) upon excitation of 800 nm light were developed. The key conjugated …
(λmax≈ 720 nm) upon excitation of 800 nm light were developed. The key conjugated …
High flux passive imaging with single-photon sensors
Single-photon avalanche diodes (SPADs) are an emerging technology with a unique
capability of capturing individual photons with high timing precision. SPADs are being used …
capability of capturing individual photons with high timing precision. SPADs are being used …
Connecting mitochondrial dynamics and life-or-death events via Bcl-2 family proteins
A Aouacheria, S Baghdiguian, HM Lamb… - Neurochemistry …, 2017 - Elsevier
The morphology of a population of mitochondria is the result of several interacting dynamical
phenomena, including fission, fusion, movement, elimination and biogenesis. Each of these …
phenomena, including fission, fusion, movement, elimination and biogenesis. Each of these …
Fluorescence anisotropy imaging in drug discovery
C Vinegoni, PF Feruglio, I Gryczynski… - Advanced drug delivery …, 2019 - Elsevier
Non-invasive measurement of drug-target engagement can provide critical insights in the
molecular pharmacology of small molecule drugs. Fluorescence polarization/fluorescence …
molecular pharmacology of small molecule drugs. Fluorescence polarization/fluorescence …
Imaging the pharmacology of nanomaterials by intravital microscopy: Toward understanding their biological behavior
MA Miller, R Weissleder - Advanced drug delivery reviews, 2017 - Elsevier
Therapeutic nanoparticles (NPs) can deliver cytotoxic chemotherapeutics and other drugs
more safely and efficiently to patients; furthermore, selective delivery to target tissues can …
more safely and efficiently to patients; furthermore, selective delivery to target tissues can …
The modulo Radon transform and its inversion
A Bhandari, M Beckmann… - 2020 28th European …, 2021 - ieeexplore.ieee.org
In this paper, we introduce the Modulo Radon Transform (MRT) which is complemented by
an inversion algorithm. The MRT generalizes the conventional Radon Transform and is …
an inversion algorithm. The MRT generalizes the conventional Radon Transform and is …
152-dB dynamic range with a large-area custom-technology single-photon avalanche diode
F Ceccarelli, G Acconcia, I Labanca… - IEEE Photonics …, 2018 - ieeexplore.ieee.org
In this letter, we demonstrate a dynamic range as high as 152 dB with a detection head
based on a single-photon avalanche diode (SPAD). This result has been attained by …
based on a single-photon avalanche diode (SPAD). This result has been attained by …
[HTML][HTML] Multi-exposure microscopic image fusion-based detail enhancement algorithm
Traditional microscope imaging techniques are unable to retrieve the complete dynamic
range of a diatom species with complex silica-based cell walls and multi-scale patterns. In …
range of a diatom species with complex silica-based cell walls and multi-scale patterns. In …