The role and activity of SWI/SNF chromatin remodelers
T Bieluszewski, S Prakash, T Roulé… - Annual Review of Plant …, 2023 - annualreviews.org
SWITCH deficient SUCROSE NONFERMENTING (SWI/SNF) class chromatin remodeling
complexes (CRCs) use the energy derived from ATP hydrolysis to facilitate access of …
complexes (CRCs) use the energy derived from ATP hydrolysis to facilitate access of …
Epigenetic mechanisms of longevity and aging
Aging is an inevitable outcome of life, characterized by progressive decline in tissue and
organ function and increased risk of mortality. Accumulating evidence links aging to genetic …
organ function and increased risk of mortality. Accumulating evidence links aging to genetic …
Epigenetic changes during aging and their reprogramming potential
AE Kane, DA Sinclair - Critical reviews in biochemistry and …, 2019 - Taylor & Francis
The aging process results in significant epigenetic changes at all levels of chromatin and
DNA organization. These include reduced global heterochromatin, nucleosome remodeling …
DNA organization. These include reduced global heterochromatin, nucleosome remodeling …
ATP-dependent chromatin remodeling: genetics, genomics and mechanisms
DC Hargreaves, GR Crabtree - Cell research, 2011 - nature.com
Macromolecular assemblies that regulate chromatin structure using the energy of ATP
hydrolysis have critical roles in development, cancer, and stem cell biology. The ATPases of …
hydrolysis have critical roles in development, cancer, and stem cell biology. The ATPases of …
Methylation of histone H3 Lys 4 in coding regions of active genes
BE Bernstein, EL Humphrey, RL Erlich… - Proceedings of the …, 2002 - National Acad Sciences
Posttranslational modifications of histone tails regulate chromatin structure and transcription.
Here we present global analyses of histone acetylation and histone H3 Lys 4 methylation …
Here we present global analyses of histone acetylation and histone H3 Lys 4 methylation …
Chromatin remodelling: the industrial revolution of DNA around histones
A Saha, J Wittmeyer, BR Cairns - Nature reviews Molecular cell biology, 2006 - nature.com
Chromatin remodellers are specialized multi-protein machines that enable access to
nucleosomal DNA by altering the structure, composition and positioning of nucleosomes. All …
nucleosomal DNA by altering the structure, composition and positioning of nucleosomes. All …
Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization
The association of genes with the nuclear pore complex (NPC) and nuclear transport factors
has been implicated in transcriptional regulation. We therefore examined the association of …
has been implicated in transcriptional regulation. We therefore examined the association of …
[HTML][HTML] A library of yeast transcription factor motifs reveals a widespread function for Rsc3 in targeting nucleosome exclusion at promoters
The sequence specificity of DNA-binding proteins is the primary mechanism by which the
cell recognizes genomic features. Here, we describe systematic determination of yeast …
cell recognizes genomic features. Here, we describe systematic determination of yeast …
High-resolution DNA-binding specificity analysis of yeast transcription factors
Transcription factors (TFs) regulate the expression of genes through sequence-specific
interactions with DNA-binding sites. However, despite recent progress in identifying in vivo …
interactions with DNA-binding sites. However, despite recent progress in identifying in vivo …