Vaccine targets against Moraxella catarrhalis

D Ren, ME Pichichero - Expert opinion on therapeutic targets, 2016 - Taylor & Francis
Introduction: Moraxella catarrhalis is a prominent pathogen that causes acute otitis media in
children and lower respiratory tract infections in adults, resulting in a significant …

Moraxella Catarrhalis: From Interactions with the Host Immune System to Vaccine Development

YC Su, B Singh, K Riesbeck - Future microbiology, 2012 - Taylor & Francis
Moraxella catarrhalis is a human-restricted commensal that over the last two decades has
developed into an emerging respiratory tract pathogen. The bacterial species is equipped …

[HTML][HTML] Virulence factors of Moraxella catarrhalis outer membrane vesicles are major targets for cross-reactive antibodies and have adapted during evolution

D Augustyniak, R Seredyński, S McClean… - Scientific reports, 2018 - nature.com
Moraxella catarrhalis is a common human respiratory tract pathogen. Its virulence factors
associated with whole bacteria or outer membrane vesicles (OMVs) aid infection …

The strongest resistance of Staphylococcus aureus to erythromycin is caused by decreasing uptake of the antibiotic into the cells

E Piątkowska, J Piątkowski… - Cellular & molecular …, 2012 - Springer
The consequence of excessive use of macrolides is a high occurrence of mechanisms
responsible for resistance to these drugs. Of 97 erythromycin-resistant bacterial strains …

Reduction of Salmonella Enteritidis Number After Infections by Immunization of Liposome-Associated Recombinant SefA

Y Pang, Y Zhang, H Wang, J Jin, J Piao… - Avian …, 2013 - meridian.allenpress.com
In order to generate Salmonella enterica serovar Enteritidis (Salmonella Enteritidis) fimbriae,
SEF14, the sefA gene, which encodes the main subunit of the SEF14 fimbrial protein, was …

Defensive and offensive cross-reactive antibodies elicited by pathogens: The good, the bad and the ugly

D Augustyniak, G Majkowska-Skrobek… - Current medicinal …, 2017 - ingentaconnect.com
Understanding how immunity to pathogens develops is crucial for progress in the quest for
effective vaccines. Intraspecies and interspecies cross-reacting antibodies are produced in …

Panel 6: vaccines

SI Pelton, MM Pettigrew… - … —Head and Neck …, 2013 - journals.sagepub.com
Objective To update progress on the effectiveness of vaccine for prevention of acute otitis
media (AOM) and identification of promising candidate antigens against Streptococcus …

[HTML][HTML] The Direct Anti-Virulence but Not Bactericidal Activity of Human Neutrophil Elastase against Moraxella catarrhalis

J Roszkowiak, S McClean, AM Mirończuk… - International Journal of …, 2023 - mdpi.com
Neutrophil elastase (NE) contributes to innate antibacterial defense at both the intracellular
(phagocytosis) and extracellular (degranulation, NETosis) levels. Moraxella catarrhalis, a …

Application of zwitterionic detergent to the solubilization of Klebsiella pneumoniae outer membrane proteins for two-dimensional gel electrophoresis

I Bednarz-Misa, P Serek, B Dudek, A Pawlak… - Journal of …, 2014 - Elsevier
Klebsiella pneumoniae is a frequent cause of nosocomial respiratory, urinary and
gastrointestinal tract infections and septicemia with the multidrug-resistant K. pneumoniae …

Bactericidal, opsonophagocytic and anti-adhesive effectiveness of cross-reactive antibodies against Moraxella catarrhalis

D Augustyniak, M Piekut… - Pathogens and …, 2015 - academic.oup.com
Moraxella catarrhalis is a human-restricted significant respiratory tract pathogen. The
bacteria accounts for 15–20% of cases of otitis media in children and is an important …