Epidermolysis bullosa (EB) is an inherited, heterogeneous group of rare genetic dermatoses
characterized by mucocutaneous fragility and blister formation, inducible by often minimal …

Background Several new genes and clinical subtypes have been identified since the
publication in 2014 of the report of the last International Consensus Meeting on …

Junctional epidermolysis bullosa (JEB) is a severe and often lethal genetic disease caused
by mutations in genes encoding the basement membrane component laminin-332 …

Cell–cell junctions link cells to each other in tissues, and regulate tissue homeostasis in
critical cell processes that include tissue barrier function, cell proliferation, and migration …

Despite many reports of putative stem-cell-based treatments in genetic and degenerative
disorders or severe injuries, the number of proven stem cell therapies has remained small …

Extracellular vesicles (EVs) derived from stem and progenitor cells may have therapeutic
effects comparable to their parental cells and are considered promising agents for the …

Importance Accurate estimation of the incidence and prevalence of each subtype of
epidermolysis bullosa (EB) is essential before clinical trials can be designed and sufficient …

Hemidesmosomes are multiprotein complexes that facilitate the stable adhesion of basal
epithelial cells to the underlying basement membrane. The mechanical stability of …

The basement membrane is a thin but dense, sheet-like specialized type of extracellular
matrix that has remarkably diverse functions tailored to individual tissues and organs. Tightly …

Biomolecules | Free Full-Text | The Human Epidermal Basement Membrane: A Shaped and
Cell Instructive Platform That Aging Slowly Alters Next Article in Journal 1-(3-Tert-Butylphenyl)-2,2,2-Trifluoroethanone …