The neural diathesis-stress model of schizophrenia revisited: An update on recent findings considering illness stage and neurobiological and methodological …

M Pruessner, AE Cullen, M Aas, EF Walker - … & Biobehavioral Reviews, 2017 - Elsevier
Over the past decade, our understanding of the role of stress in serious mental illness has
become more sophisticated. In this paper, we revisit the neural diathesis-stress model of …

[HTML][HTML] A systematic review of the activity of the hypothalamic–pituitary–adrenal axis in first episode psychosis

S Borges, C Gayer-Anderson, V Mondelli - Psychoneuroendocrinology, 2013 - Elsevier
Up to now studies on hypothalamic–pituitary–adrenal (HPA) axis activity in psychosis have
shown inconsistent findings. These inconsistencies have been often ascribed to …

The traumagenic neurodevelopmental model of psychosis revisited

J Read, R Fosse, A Moskowitz, B Perry - Neuropsychiatry, 2014 - pure.au.dk
Evidence that childhood adversities are risk factors for psychosis has accumulated rapidly.
Research into the mechanisms underlying these relationships has focused, productively, on …

A high-resolution in vivo magnetic resonance imaging atlas of the human hypothalamic region

C Neudorfer, J Germann, GJB Elias, R Gramer… - Scientific data, 2020 - nature.com
The study of the hypothalamus and its topological changes provides valuable insights into
underlying physiological and pathological processes. Owing to technological limitations …

Using deep autoencoders to identify abnormal brain structural patterns in neuropsychiatric disorders: A large‐scale multi‐sample study

WHL Pinaya, A Mechelli, JR Sato - Human brain mapping, 2019 - Wiley Online Library
Abstract Machine learning is becoming an increasingly popular approach for investigating
spatially distributed and subtle neuroanatomical alterations in brain‐based disorders …

Hyperprolactinemia in antipsychotic-naive patients with first-episode psychosis

A Riecher-Rössler, JK Rybakowski… - Psychological …, 2013 - cambridge.org
BackgroundHyperprolactinemia is frequent in patients with schizophrenic psychoses. It is
usually regarded as an adverse effect of antipsychotics but has recently also been shown in …

Neuroendocrine profile in a rat model of psychosocial stress: relation to oxidative stress

M Colaianna, S Schiavone, M Zotti, P Tucci… - Antioxidants & redox …, 2013 - liebertpub.com
Aims: Psychosocial stress alters the hypothalamic-pituitary-adrenal axis (HPA-axis).
Increasing evidence shows a link between these alterations and oxidant elevation. Oxidative …

Molecular substrates of schizophrenia: homeostatic signaling to connectivity

MA Landek-Salgado, TE Faust, A Sawa - Molecular psychiatry, 2016 - nature.com
Schizophrenia (SZ) is a devastating psychiatric condition affecting numerous brain systems.
Recent studies have identified genetic factors that confer an increased risk of SZ and …

Hypothalamic volume and asymmetry in the pediatric population: a retrospective MRI study

S Isıklar, S Turan Ozdemir, G Ozkaya… - Brain Structure and …, 2022 - Springer
This study investigated age-and sex-related changes in the volumetric development and
asymmetry of the normal hypothalamus from birth to 18. Individuals aged 0–18 with MRI …

Diverse definitions of the early course of schizophrenia—a targeted literature review

R Newton, A Rouleau, AG Nylander, JY Loze… - npj …, 2018 - nature.com
Schizophrenia is a debilitating psychiatric disorder and patients experience significant
comorbidity, especially cognitive and psychosocial deficits, already at the onset of disease …