[HTML][HTML] Transgenic mouse overexpressing Spermine oxidase in Cerebrocortical neurons: astrocyte dysfunction and susceptibility to epileptic seizures

M Marcoli, C Cervetto, S Amato, C Fiorucci, G Maura… - Biomolecules, 2022 - mdpi.com
Polyamines are organic polycations ubiquitously present in living cells. Polyamines are
involved in many cellular processes, and their content in mammalian cells is tightly …

[HTML][HTML] Brazilian Theraphosidae: a toxicological point of view

KWR Macedo, LJL Costa, JO Souza… - Journal of Venomous …, 2021 - SciELO Brasil
The Theraphosidae family includes the largest number of species of the Mygalomorphae
infraorder, with hundreds of species currently catalogued. However, there is a huge lack on …

Acanthoscurria gomesiana spider‐derived Mygalin in the prelimbic prefrontal cortex modulates neuropathic pain and depression comorbid

AC Medeiros, P Medeiros, RN Ruggiero… - … of Biochemical and …, 2023 - Wiley Online Library
Depression has a high rate of comorbidity with neuropathic pain. This study aims to
investigate the effect of Mygalin, an acylpolyamine synthesized from a natural molecule in …

Acanthoscurria gomesiana spider‐derived synthetic mygalin in the dorsal raphe nucleus modulates acute and chronic pain

AC Medeiros, P Medeiros, RL de Freitas… - … of Biochemical and …, 2021 - Wiley Online Library
Mygalin, a diacylspermidine that is naturally found in the hemolymph of the spider
Acanthoscurria gomesiana, is of interest for development as a potential analgesic. Previous …

[PDF][PDF] Hemolymph and hemocytes of Tarantula spiders: Physiological roles and potential as sources of Bioactive molecules

T Soares, TH Napoleão, FRB Ferreira… - Advances in Animal …, 2015 - novapublishers.com
Arachnids compose the most important and numerous group of chelicerates and include
spiders, scorpions, mites and ticks. Some arachnids have a worldwide distribution and can …

[PDF][PDF] Studying the Excitatory and Inhibitory Neurotransmissions with Spider Venoms

JL Liberato, WF dos Santos - Spider Venoms, 2016 - researchgate.net
Spider venoms are a complex cocktail containing hundreds of biologically active
compounds resulting in a potent weapon to subdue their prey and for predator deterrence …