Designing therapeutics is a process with many challenges. Even if the first hurdle—
designing a drug that modulates the action of a particular biological target in vitro—is …

Oral administration is the most commonly used and readily accepted form of drug delivery;
however, it is find that many drugs are difficult to attain enough bioavailability when …

Abstract pH-responsive polymers contain ionic functional groups as pendants in their
structure. The total number of charged groups on polymer chains determines the overall …

The present report focuses on the various aspects of oral delivery of anticancer drugs. The
significance of oral delivery in cancer therapeutics has been highlighted which principally …

Titratable polyanions, and more particularly polymers bearing carboxylate groups, have
been used in recent years to produce a variety of pH-sensitive colloids. These polymers …

Importance of the field: Spontaneously constructed from block copolymers in aqueous
media, the polymer micelle has been extensively studied as a potential carrier of poorly …

Nanotechnology, in health and medicine, extensively improves the safety and efficacy of
different therapeutic agents, particularly the aspects related to drug delivery and targeting …

Cancer is an extremely complex disease involving multiple signaling pathways that enable
tumor cells to evade programmed cell death, thus making cancer treatment extremely …

In the case of chronic therapies, the oral route is often the preferred route for drug
administration given its acceptability and convenience. However, various factors which limit …

Nano polymeric micelles (nano PMs) help to increase accessibility to tumor sites, decrease
side effects and allow controlled drug dissemination over a long period of time. The aim of …