Pathogenesis and treatment options of cancer related anemia: perspective for a targeted mechanism-based approach

C Madeddu, G Gramignano, G Astara… - Frontiers in …, 2018 - frontiersin.org
Cancer-related anemia (CRA) is a common sign occurring in more than 30% of cancer
patients at diagnosis before the initiation of antineoplastic therapy. CRA has a relevant …

Hereditary spherocytosis, elliptocytosis, and other red cell membrane disorders

L Da Costa, J Galimand, O Fenneteau, N Mohandas - Blood reviews, 2013 - Elsevier
Hereditary spherocytosis and elliptocytosis are the two most common inherited red cell
membrane disorders resulting from mutations in genes encoding various red cell membrane …

Microneedle patches loaded with nanovesicles for glucose transporter-mediated insulin delivery

Q Chen, Z Xiao, C Wang, G Chen, Y Zhang, X Zhang… - ACS …, 2022 - ACS Publications
Glucose-responsive insulin delivery systems that mimic insulin secretion activity in the
pancreas show great potential to improve clinical therapeutic outcomes for people with type …

The active role of vitamin C in mammalian iron metabolism: much more than just enhanced iron absorption!

DJR Lane, DR Richardson - Free radical biology and medicine, 2014 - Elsevier
Ascorbate is a cofactor in numerous metabolic reactions. Humans cannot synthesize
ascorbate owing to inactivation of the gene encoding the enzyme l-gulono-γ-lactone …

Glucose and glutamine metabolism regulate human hematopoietic stem cell lineage specification

L Oburoglu, S Tardito, V Fritz, SC De Barros, P Merida… - Cell stem cell, 2014 - cell.com
The metabolic state of quiescent hematopoietic stem cells (HSCs) is an important regulator
of self-renewal, but it is unclear whether or how metabolic parameters contribute to HSC …

Red blood cells for glucose‐responsive insulin delivery

C Wang, Y Ye, W Sun, J Yu, J Wang… - Advanced …, 2017 - Wiley Online Library
Glucose‐responsive delivery of insulin mimicking the function of pancreatic β‐cells to
achieve meticulous control of blood glucose (BG) would revolutionize diabetes care. Here …

Cellular pathways for transport and efflux of ascorbate and dehydroascorbate

A Corti, AF Casini, A Pompella - Archives of biochemistry and biophysics, 2010 - Elsevier
The mechanisms allowing the cellular transport of ascorbic acid represent a primary aspect
for the understanding of the roles played by this vitamin in pathophysiology. Considerable …

Potential role of sugar transporters in cancer and their relationship with anticancer therapy

MB Calvo, A Figueroa, EG Pulido… - International journal …, 2010 - Wiley Online Library
Sugars, primarily glucose and fructose, are the main energy source of cells. Because of their
hydrophilic nature, cells use a number of transporter proteins to introduce sugars through …

Role of monosaccharide transport proteins in carbohydrate assimilation, distribution, metabolism, and homeostasis

AJ Cura, A Carruthers - Comprehensive Physiology, 2011 - Wiley Online Library
The facilitated diffusion of glucose, galactose, fructose, urate, myoinositol, and
dehydroascorbic acid in mammals is catalyzed by a family of 14 monosaccharide transport …

Is there a direct role for erythrocytes in the immune response?

D Morera, SA MacKenzie - Veterinary research, 2011 - Springer
Erythrocytes are highly abundant circulating cells in the vertebrates, which, with the notable
exception of mammals, remain nucleated throughout the entire life cycle. The major function …