Compositional assessment of bone by Raman spectroscopy

M Unal, R Ahmed, A Mahadevan-Jansen, JS Nyman - Analyst, 2021 - pubs.rsc.org
Raman spectroscopy (RS) is used to analyze the physiochemical properties of bone
because it is non-destructive and requires minimal sample preparation. With over two …

[HTML][HTML] Applications of vibrational spectroscopy for analysis of connective tissues

W Querido, S Kandel, N Pleshko - Molecules, 2021 - mdpi.com
Advances in vibrational spectroscopy have propelled new insights into the molecular
composition and structure of biological tissues. In this review, we discuss common …

Germ‐Free C57BL/6 Mice Have Increased Bone Mass and Altered Matrix Properties but Not Decreased Bone Fracture Resistance

G Vahidi, M Moody, HD Welhaven… - Journal of Bone and …, 2023 - academic.oup.com
The gut microbiome impacts bone mass, which implies a disruption to bone homeostasis.
However, it is not yet clear how the gut microbiome affects the regulation of bone mass and …

Fracture toughness: bridging the gap between hip fracture and fracture risk assessment

D Dapaah, DR Martel, F Iranmanesh… - Current Osteoporosis …, 2023 - Springer
Abstract Purpose of Review This review surveys recent literature related to cortical bone
fracture mechanics and its application towards understanding bone fragility and hip …

Assessing bone maturity: compositional and mechanical properties of rib cortical bone at different ages

A Bonicelli, EF Kranioti, B Xhemali, E Arnold, P Zioupos - Bone, 2022 - Elsevier
Understanding what maturity entails for bone, when it arrives, and its pre-and post-maturity
traits and properties are very important for understanding its evolution and physiology. There …

Fundamentals and Applications of Raman‐Based Techniques for the Design and Development of Active Biomedical Materials

Á Fernández‐Galiana, O Bibikova… - Advanced …, 2023 - Wiley Online Library
Raman spectroscopy is an analytical method based on light–matter interactions that can
interrogate the vibrational modes of matter and provide representative molecular …

Sensitivity of the amide I band to matrix manipulation in bone: a Raman micro-spectroscopy and spatially offset Raman spectroscopy study

R Ahmed, M Unal, R Gautam, S Uppuganti, S Derasari… - Analyst, 2023 - pubs.rsc.org
The fracture resistance of bone arises from the hierarchical arrangement of minerals,
collagen fibrils (ie, cross-linked triple helices of α1 and α2 collagen I chains), non …

Bone remodeling and bone matrix quality before and after menopause in healthy women

D Farlay, Y Bala, S Rizzo, S Bare, JM Lappe, R Recker… - Bone, 2019 - Elsevier
Acceleration of remodeling activity after menopause leads to bone loss and fragility,
however, whether this is associated with modifications of bone matrix quality has been less …

Induction and rescue of skeletal fragility in a high-fat diet mouse model of type 2 diabetes: An in vivo and in vitro approach

JE LLabre, GE Sroga, MJL Tice, D Vashishth - Bone, 2022 - Elsevier
Poor bone quality is associated with Type 2 Diabetes (T2D), with patients having a higher
risk of fracture despite normal to high bone mineral density (BMD). Diabetes contributes to …

The age-related decrease in material properties of BALB/c mouse long bones involves alterations to the extracellular matrix

A Creecy, S Uppuganti, MR Girard, SG Schlunk… - Bone, 2020 - Elsevier
One possibility for the disproportionate increase in fracture risk with aging relative to the
decrease in bone mass is an accumulation of changes to the bone matrix which …