Epidemiological and biological plausibility studies support a cause-and-effect relationship
between increased levels of physical activity or cardiorespiratory fitness and reduced …

Epidemiological evidence suggests that the incidence of ischaemic stroke in young adults
(18–50 years) has increased substantially. These patients have a long life expectancy after …

Stroke has multiple etiologies, but the underlying genes and pathways are largely unknown.
We conducted a multiancestry genome-wide-association meta-analysis in 521,612 …

Biologic sex influences many variables that are important to brain health in general, and to
stroke or cerebral ischemia in particular, such as general health status, cerebrovascular …

Ischaemic stroke at young age is an increasing problem in both developing and developed
countries due to rising incidence, high morbidity and mortality and long-term psychological …

730 Stroke March 2020 migraine with aura is associated with an≈ 2-fold increase in risk of
ischemic stroke. 20, 21 However, the combination of all 3 risk factors (migraine with aura …

Objective To investigate incidence of stroke and its subtypes in young adults, according to
sex and age, and to study trends over time. Methods We established a nationwide cohort …

Importance While stroke mortality rates have decreased substantially in the past 2 decades,
this trend has been primarily limited to older adults. Increasing trends in stroke incidence …

Strokes in young adults are reported as being uncommon, comprising 10%–15% of all
stroke patients. However, compared with stroke in older adults, stroke in the young has a …

Abstract This third Guideline for Reasonable and Appropriate Care in the Emergency
Department (GRACE‐3) from the Society for Academic Emergency Medicine is on the topic …