The chemistry, biochemistry, pharmacology and molecular biology of oxylipins (defined as a
family of oxygenated natural products that are formed from unsaturated fatty acids by …

Endogenous bioactive lipids are part of a complex network that modulates a plethora of
cellular and molecular processes involved in health and disease, of which inflammation …

Lipid droplets are fat storage organelles present in most eukaryotic cells. They consist of a
neutral lipid core containing mostly triglycerides and sterol esters and covered by a …

In the past few decades, as a result of their anti-inflammatory properties, n-3 long chain
polyunsaturated fatty acids (n-3 LC-PUFAs), have gained greater importance in the …

Marine organisms are an important source of natural products with unique and diverse
chemical structures that may hold the key for the development of novel drugs …

A western type diet and lifestyle play an important role in the development of chronic
diseases, yet little insight into the precise cellular and biomolecular mechanisms has …

PCOS as the most common endocrine disorder of women in their reproductive age affects
between 5–15% of the female population. Apart from its cardinal symptoms, like irregular …

This review provides evidence for the importance of white and brown adipose tissue (ie WAT
and BAT) function for the maintenance of healthy metabolic phenotype and its preservation …

The prototypic proinflammatory cytokine IL-1β plays a central role in innate immunity and
inflammatory disorders. The formation of mature IL-1β from an inactive pro-IL-1β precursor is …

Chronic inflammation has been implicated in the pathophysiology of major depressive
disorder (MDD). Activating the resolution of inflammation through ω-3 fatty acid …