The ability of physicians to effectively treat and cure cancer is directly dependent on their
ability to detect cancers at their earliest stages. Proteomic analyses of early-stage cancers …

Any tissue is made up of a heterogeneous mix of spatially distributed cell types. In response
to any (patho) physiological cue, responses of each cell type in any given tissue may be …

Spectral analyses of an uninterrupted 5.5-million-year (My)–long chronology of late
Oligocene–early Miocene climate and ocean carbon chemistry from two deep-sea cores …

In both ageing men and women, lower urinary tract symptoms (LUTS) are increasing. These
infections have many possible causes, including smooth muscle dysfunction, neurological …

BACKGROUND The widespread use of prostate‐specific antigen (PSA) screening has had
a tremendous impact on all aspects of the management of prostate carcinoma. Although …

Urine protein profiling with surface-enhanced laser-desorption/ionization time-of-flight mass
spectrometry. Background In the last few years there has been an increasing interest in …

Background The early detection of ovarian cancer has the potential to dramatically reduce
mortality. Recently, the use of mass spectrometry to develop profiles of patient serum …

Background: Protein expression profiling for differences indicative of early cancer has
promise for improving diagnostics. This report describes the first stage of a National Cancer …

Objective: Pathological changes in an organ or tissue may be reflected in proteomic patterns
in serum. It is possible that unique serum proteomic patterns could be used to discriminate …

Recent reports from our laboratory and others support the SELDI ProteinChip technology as
a potential clinical diagnostic tool when combined with n‐dimensional analyses algorithms …