Immunotoxic and hepatotoxic effects of perfluoro-n-decanoic acid (PFDA) on female Harlan Sprague–Dawley rats and B6C3F1/N mice when administered by oral …

RP Frawley, M Smith, MF Cesta… - Journal of …, 2018 - Taylor & Francis
Poly-and perfluoroalkyl substances (PFAS) are chemically and thermally stable,
hydrophobic, lipophobic compounds used in stain repellants and water and oil surfactants …

Route-dependent systemic and local immune effects following exposure to solutions prepared from titanium dioxide nanoparticles

W Auttachoat, CE McLoughlin, KL White Jr… - Journal of …, 2014 - Taylor & Francis
Nanoparticle titanium dioxide (nano-TiO2) is a white pigment widely used in foods,
sunscreens, and other cosmetic products. However, it remains unclear whether exposure to …

Respiratory toxicity and immunotoxicity evaluations of microparticle and nanoparticle C60 fullerene aggregates in mice and rats following nose-only inhalation for 13 …

BC Sayers, DR Germolec, NJ Walker… - …, 2016 - Taylor & Francis
Abstract C60 fullerene (C60), or buckminsterfullerene, is a spherical arrangement of 60
carbon atoms, having a diameter of approximately 1 nm, and is produced naturally as a by …

Evaluation of immunotoxicity of sodium metavanadate following drinking water exposure in female B6C3F1/N mice in a 28‐day study

R Frawley, VJ Johnson, GR Burleson… - Journal of Applied …, 2023 - Wiley Online Library
Sodium metavanadate (NaVO3) is a pentavalent vanadium compound used in the metal
industry and dietary supplements; human exposure occurs through inhalation of fumes and …

Immunomodulatory effects of black cohosh (Actaea racemosa) extract in female B6C3F1/N mice

MJ Smith, DR Germolec, RP Frawley, KL White Jr - Toxicology, 2013 - Elsevier
Black cohosh extracts (BCE; Actaea racemosa) are being used worldwide as an alternative
to hormone replacement therapy for the management of menstrual and menopausal …

Immunotoxic effects of sodium tungstate dihydrate on female B6C3F1/N mice when administered in drinking water

RP Frawley, MJ Smith, KL White Jr… - Journal of …, 2016 - Taylor & Francis
Tungsten is a naturally occurring, high-tensile strength element that has been used in a
number of consumer products. Tungsten has been detected in soil, waterways, groundwater …

Nuclear factor of activated T cells as a marker of in vivo low‐dose dibenzo[a,h]anthracene exposure

C He, M Shen, K Morita, D Wang… - Journal of Applied …, 2020 - Wiley Online Library
We previously demonstrated that particulate matter≤ 2.5 μm (PM2. 5) suppresses the
immune response in the spleen in vivo. Although PM2. 5 includes the polycyclic aromatic …

Research Progress on Immunotoxic Mechanism of Dioxins and Dioxin-like Pollutants.

W Xinge, L Na, H Yingnan, M Mei… - Asian Journals of …, 2023 - search.ebscohost.com
Dioxins are highly potent exogenous ligands of aryl hydrocarbon receptor (AHR), which are
known to exert immunotoxic effects through AHR. The canonical AHR toxicity pathway is that …

Field Study for PAH Absorption Performances of Butyl Rubber, PDMS, and SPMD Passive Samplers

OE Tureyen, SD Yakan, A Yilmaz, B Yetiskin, O Okay… - 2021 - researchsquare.com
Polycyclic aromatic hydrocarbons (PAHs) are organic pollutants having various adverse
effects on the marine ecosystem. Because of their low solubility in the marine environment …

[PDF][PDF] DRAFT AOP 277: Impaired Interleukin-1 Receptor Type I (IL-1R1) signaling leading to Impaired T-Cell Dependent Antibody Response

N Delrue - oecd.org
The pleiotropic cytokine IL-1 mediates its biological functions via association with the
signaling receptor IL-1R1. These may include initiation of innate immunity as well as …