Evaluation of methods for the prediction of membrane spanning regions
S Möller, MDR Croning, R Apweiler - Bioinformatics, 2001 - academic.oup.com
Motivation: A variety of tools are available to predict the topology of transmembrane proteins.
To date no independent evaluation of the performance of these tools has been published. A …
To date no independent evaluation of the performance of these tools has been published. A …
Basic charge clusters and predictions of membrane protein topology
The topology predictor SPLIT 4.0 (http://pref. etfos. hr) predicts the sequence location of
transmembrane helices by performing an automatic selection of optimal amino acid attribute …
transmembrane helices by performing an automatic selection of optimal amino acid attribute …
Knowledge-based computational methods for identifying or designing novel, non-homologous antimicrobial peptides
We describe computational approaches for identifying promising lead candidates for the
development of peptide antibiotics, in the context of quantitative structure–activity …
development of peptide antibiotics, in the context of quantitative structure–activity …
Hydrophobic interactions drive ligand-receptor recognition for activation and inhibition of staphylococcal quorum sensing
Two-component systems represent the most widely used signaling paradigm in living
organisms. Encoding the prototypical two-component system in Gram-positive bacteria, the …
organisms. Encoding the prototypical two-component system in Gram-positive bacteria, the …
[HTML][HTML] Computational approaches for revealing the structure of membrane transporters: case study on bilitranslocase
K Venko, AR Choudhury, M Novič - Computational and structural …, 2017 - Elsevier
The structural and functional details of transmembrane proteins are vastly underexplored,
mostly due to experimental difficulties regarding their solubility and stability. Currently, the …
mostly due to experimental difficulties regarding their solubility and stability. Currently, the …
[HTML][HTML] Homology modeling of human CCR5 and analysis of its binding properties through molecular docking and molecular dynamics simulation
In this study, homology modeling, molecular docking and molecular dynamics simulation
were performed to explore structural features and binding mechanism of some inhibitors of …
were performed to explore structural features and binding mechanism of some inhibitors of …
Mutation in mitochondrial complex I ND6 subunit is associated with defective response to hypoxia in human glioma cells
C DeHaan, B Habibi-Nazhad, E Yan, N Salloum… - Molecular Cancer, 2004 - Springer
Background Hypoxia-tolerant human glioma cells reduce oxygen consumption rate in
response to oxygen deficit, a defense mechanism that contributes to survival under …
response to oxygen deficit, a defense mechanism that contributes to survival under …
[图书][B] Bioenergetics: a bridge across life and universe
D Juretic - 2021 - taylorfrancis.com
Bioenergetics deals with the very first energy transformation steps performed by living cells.
Increased dissipation is the primary effect of processing external energy packages. Enzyme …
Increased dissipation is the primary effect of processing external energy packages. Enzyme …
[HTML][HTML] Designed peptide with a flexible central motif from ranatuerins adapts its conformation to bacterial membranes
The long-standing goal in the field of peptide antibiotics has been to design lead
compounds that have a wide spectrum of excellent antibacterial activity but are nontoxic to …
compounds that have a wide spectrum of excellent antibacterial activity but are nontoxic to …
Comparative genomics of serotype Asia 1 foot-and-mouth disease virus isolates from India sampled over the last two decades
This study deals with a comparative analysis of complete genome sequences of twenty-one
serotype Asia 1 foot-and-mouth disease (FMD) field viruses isolated over a period of two …
serotype Asia 1 foot-and-mouth disease (FMD) field viruses isolated over a period of two …