Oils and fats are the most important renewable raw materials for the chemical industry.
Hitherto, industrial oleochemistry has concentrated predominantly on the carboxy …

RNA is a versatile biological macromolecule that is crucial in mobilizing and interpreting our
genetic information. It is not surprising then that researchers have sought to exploit the …

An activity that unwinds double-stranded RNA has been reported to exist in several
organisms. We have analyzed the RNA intermediates and final products of the unwinding …

Agrobacterium tumefaciens is capable of transferring a defined piece of DNA (T-DNA)
containing tumorigenic loci from its tumor-inducing (Ti) plasmid into the genome of a large …

We have attempted to use antisense RNA techniques in the developing Xenopus embryo
and found that although hybrids form between sense and antisense RNAs, they are …

A family of oligonucleotides and phosphorothioate oligonucleotide analogues was
synthesized with a cholesteryl group tethered at the 3'-terminal internucleoside link. This …

Polygalacturonase [PG; poly (1, 4-α-D-galacturonide) glycanhydrolase; EC 3.2. 1.15] is
expressed in tomato only during the ripening stage of fruit development. PG becomes …

Amphibian eggs and embryos as well as mammalian cells have been reported to contain an
activity that unwinds double-stranded RNA. We have now found that adenosine residues …

The mechanism of hybrid-arrested translation by antisense oligodeoxynucleotides has been
investigated with the rabbit reticulocyte lysate system. The oligonucleotides studied were …

Overexpression of TAR-containing sequences (TAR decoys) was used to render cells
resistant to HIV replication. A chimeric tRNAmr-TAR transcription unit contained in a double …