Reactive oxygen species‐regulating strategies based on nanomaterials for disease treatment

C Zhang, X Wang, J Du, Z Gu, Y Zhao - Advanced Science, 2021 - Wiley Online Library
Reactive oxygen species (ROS) play an essential role in physiological and pathological
processes. Studies on the regulation of ROS for disease treatments have caused wide …

Role of antioxidants in prophylaxis and therapy: A pharmaceutical perspective

DV Ratnam, DD Ankola, V Bhardwaj… - Journal of controlled …, 2006 - Elsevier
Antioxidants are emerging as prophylactic and therapeutic agents. These are the agents,
which scavenge free radicals otherwise reactive oxygen species and prevent the damage …

Nanotechnology, nanotoxicology, and neuroscience

WH Suh, KS Suslick, GD Stucky, YH Suh - Progress in neurobiology, 2009 - Elsevier
Nanotechnology, which deals with features as small as a 1 billionth of a meter, began to
enter into mainstream physical sciences and engineering some 20 years ago. Recent …

Antioxidative nanomaterials and biomedical applications

Y Liu, J Shi - Nano Today, 2019 - Elsevier
Highlights•This review article offers an in-depth overview of significant advances in the field
of antioxidative nanotechnology.•The pathology and molecular mechanisms of oxidative …

Wielding the double-edged sword: Redox drug delivery systems for inflammatory bowel disease

Y Chen, M Shui, Q Yuan, CT Vong, Z Yang… - Journal of Controlled …, 2023 - Elsevier
The etiology of inflammatory bowel disease (IBD) is extremely complex and related to an
excessive immune response that results in the pathologically release of reactive oxygen …

[HTML][HTML] Islet transplantation and encapsulation: an update on recent developments

V Vaithilingam, BE Tuch - The review of diabetic studies: RDS, 2011 - ncbi.nlm.nih.gov
Human islet transplantation can provide good glycemic control in diabetic recipients without
exogenous insulin. However, a major factor limiting its application is the recipient's need to …

Recent strategies for the immobilization of therapeutic enzymes

CY Zhu, FL Li, YW Zhang, RK Gupta, SKS Patel… - Polymers, 2022 - mdpi.com
Therapeutic enzymes play important roles in modern medicine due to their high affinity and
specificity. However, it is very expensive to use them in clinical medicine because of their …

Nano-fibrous scaffold for controlled delivery of recombinant human PDGF-BB

G Wei, Q Jin, WV Giannobile, PX Ma - Journal of Controlled Release, 2006 - Elsevier
The localized and temporally controlled delivery of growth factors is key to achieving optimal
clinical efficacy. In sophisticated tissue engineering strategies, the biodegradable scaffold is …

Oral delivery of antioxidant enzymes for effective treatment of inflammatory disease

Z Zeng, X He, C Li, S Lin, H Chen, L Liu, X Feng - Biomaterials, 2021 - Elsevier
Oral administration of protein is very challenging for therapeutic applications due to its
instability and easy degradation in the gastrointestinal tract. Herein, we reported an …

Strategies to expand the therapeutic potential of superoxide dismutase by exploiting delivery approaches

AC Rosa, N Bruni, G Meineri, D Corsi, N Cavi… - International Journal of …, 2021 - Elsevier
The overproduction of free radicals can cause oxidative-stress damage to a range of
biomolecules, and thus potentially contribute to several pathologies, from …