Lipid droplets (LDs) are organelles that have evolved to store intracellular neutral lipids and
maintain cellular energy homeostasis. Once considered as inert fat particles, they have …

The functional state of T cells is a key determinant for effective antitumor immunity and
immunotherapy. Cellular metabolism, including lipid metabolism, controls T cell …

The fact that the identity of the cells that initiate metastasis in most human cancers is
unknown hampers the development of antimetastatic therapies. Here we describe a …

Background Excess storage of lipids in ectopic tissues, such as skeletal muscle, liver, and
heart, seems to associate closely with metabolic abnormalities and cardiac disease …

Excess lipid accumulation in peripheral tissues is a key feature of many metabolic diseases.
Therefore, techniques for imaging and quantifying lipids in various tissues are important for …

Mesenchymal stem and progenitor cells (MSPCs) contribute to bone marrow (BM)
homeostasis by generating multiple types of stromal cells. MSPCs can be labeled in the …

There exists a clear clinical need for adipose tissue reconstruction strategies to repair soft
tissue defects which outperform the currently available approaches. In this respect, additive …

Background: Excess cholesterol accumulation in lesional macrophages elicits complex
responses in atherosclerosis. Epsins, a family of endocytic adaptors, fuel the progression of …

Current soft tissue repair techniques for women with breast cancer remain associated with
several drawbacks including surgical complications and a high resorption rate for lipofilling …

Visualizing and dynamic tracking lipid droplets (LDs) are of great importance to biological
research. Herein, two-photon absorption fluorescent small bioprobes based on lipophilic …