Hydrogels as functional components in artificial cell systems

ME Allen, JW Hindley, DK Baxani, O Ces… - Nature Reviews …, 2022 - nature.com
Recent years have seen substantial efforts aimed at constructing artificial cells from various
molecular components with the aim of mimicking the processes, behaviours and …

Membrane targeting cationic antimicrobial peptides

D Ciumac, H Gong, X Hu, JR Lu - Journal of colloid and interface science, 2019 - Elsevier
Many short cationic peptides are amphiphilic and are often termed antimicrobial peptides
(AMPs) as they can kill various microorganisms. These AMPs have largely been discovered …

Antibacterial action of nanoparticles by lethal stretching of bacterial cell membranes

DP Linklater, VA Baulin, X Le Guével… - Advanced …, 2020 - Wiley Online Library
It is commonly accepted that nanoparticles (NPs) can kill bacteria; however, the mechanism
of antimicrobial action remains obscure for large NPs that cannot translocate the bacterial …

Hydrophilic surface modification of PDMS for droplet microfluidics using a simple, quick, and robust method via PVA deposition

T Trantidou, Y Elani, E Parsons, O Ces - Microsystems & …, 2017 - nature.com
Polydimethylsiloxane (PDMS) is a dominant material in the fabrication of microfluidic
devices to generate water-in-oil droplets, particularly lipid-stabilized droplets, because of its …

Chemical activation of the mechanotransduction channel Piezo1

R Syeda, J Xu, AE Dubin, B Coste, J Mathur, T Huynh… - elife, 2015 - elifesciences.org
Piezo ion channels are activated by various types of mechanical stimuli and function as
biological pressure sensors in both vertebrates and invertebrates. To date, mechanical …

Piezo proteins are pore-forming subunits of mechanically activated channels

B Coste, B Xiao, JS Santos, R Syeda, J Grandl… - Nature, 2012 - nature.com
Mechanotransduction has an important role in physiology. Biological processes including
sensing touch and sound waves require as-yet-unidentified cation channels that detect …

Droplet based microfluidics

R Seemann, M Brinkmann, T Pfohl… - Reports on progress …, 2011 - iopscience.iop.org
Droplet based microfluidics is a rapidly growing interdisciplinary field of research combining
soft matter physics, biochemistry and microsystems engineering. Its applications range from …

Vesicle-based artificial cells as chemical microreactors with spatially segregated reaction pathways

Y Elani, RV Law, O Ces - Nature communications, 2014 - nature.com
In the discipline of bottom-up synthetic biology, vesicles define the boundaries of artificial
cells and are increasingly being used as biochemical microreactors operating in …

Multi-responsive hydrogel structures from patterned droplet networks

FG Downs, DJ Lunn, MJ Booth, JB Sauer… - Nature …, 2020 - nature.com
Responsive hydrogels that undergo controlled shape changes in response to a range of
stimuli are of interest for microscale soft robotic and biomedical devices. However, these …

Engineering of stimuli-responsive lipid-bilayer membranes using supramolecular systems

MJ Langton - Nature Reviews Chemistry, 2021 - nature.com
The membrane proteins found in nature control many important cellular functions, including
signal transduction and transmembrane ion transport, and these, in turn, are regulated by …